PedAM
Pediatric Disease Annotations & Medicines
| Disease | hemolytic anemia |
| Phenotype | C0002871|anemia |
| Sentences | 4 |
| PubMedID- 24385735 | Transient aplastic crisis manifests as sudden exacerbation of anemia in patients with chronic hemolytic anemia, with severe reticulocytopenia lasting 7-10 days in the absence of erythroid precursors due to lysis of the precursors by pv-b19 [4]—the hallmark of which is giant pronormoblasts in the bone marrow [5]. |
| PubMedID- 22851939 | Erythropoietin may improve anemia in patients with autoimmune hemolytic anemia associated with reticulocytopenia. |
| PubMedID- 25619350 | All the cases presented servere lymphadenopathy and hepatosplenomegaly with anemia (4 of them with hemolytic anemia) and thrombocytopenia. |
| PubMedID- 25559010 | Patients with sickle cell anemia or other forms of hemolytic anemia often develop pulmonary hypertension secondary to endothelial dysfunction.84 one of the pathogenic factors is thought to be the increased circulating ferrous heme and hemoglobin that scavenge no, a potent vasodilator, in these patients.47,85 interestingly, hemoglobin protects bacteria against no toxicity by catalyzing the dioxygenation of no to nitrate.86 based on the growing evidence of no as a major regulator of vascular homeostasis in mammals, the interaction between no and heme has become a topic of intense investigation. |
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