PedAM
Pediatric Disease Annotations & Medicines
| Disease | heart disease |
| Phenotype | C0020542|pulmonary hypertension |
| Sentences | 109 |
| PubMedID- 20595458 | Background: pulmonary artery occlusion pressure (paop) is used to differentiate patients with pulmonary hypertension (ph) associated with left-sided heart disease from other etiologies. |
| PubMedID- 20814475 | The introduction of inhaled nitric oxide (ino) has added a new dimension to the treatment of pulmonary hypertension associated with congenital heart disease. |
| PubMedID- 24566553 | Objective: to investigate preoperative and postoperative blood levels of soluble intercellular and vascular cell adhesion molecules (sicam-1, svcam-1) in patients with and without pulmonary hypertension (pah) due to congenital heart disease and left to right (l-r) shunt and to determine whether these molecules can be used as reliable prognostic markers of endothelial activity to predict surgical outcomes. |
| PubMedID- 24771555 | The majority had idiopathic pulmonary arterial hypertension (n=30); the remaining patients had pulmonary hypertension associated with repaired congenital heart disease (n=17) or lung disease (n=3). |
| PubMedID- 24460475 | Objectives: pulmonary hypertension (ph) due to left heart disease may impair outcome after heart transplantation (ht). |
| PubMedID- 25697040 | [pulmonary hypertension due to left heart diseases]. |
| PubMedID- 22837863 | Indeed, in murine models of pulmonary hypertension associated with left heart disease and in monocrotaline-induced rodent pulmonary hypertension, treatment with a mast cell stabilizer or use of mast cell deficient rats attenuated vascular remodeling. |
| PubMedID- 26202179 | There is no cure for pulmonary hypertension due to left heart disease (ph-lhd), but the rationale for using sildenafil to treat pulmonary arterial hypertension with heart failure with reduced ejection fraction (hfref) has been supported by short-term studies. |
| PubMedID- 23158820 | Conclusion: there was the expression of urotensin ii protein and mrna in the lung of pulmonary hypertension patients with congenital heart disease, and these expression may involve the formation of pulmonary hypertension of congenital heart disease. |
| PubMedID- 25840093 | Pathophysiology and clinical relevance of pulmonary remodelling in pulmonary hypertension due to left heart diseases. |
| PubMedID- 23075130 | pulmonary hypertension associated with congenital heart disease: a practical review for the pediatric cardiologist. |
| PubMedID- 20144487 | Minimum-intensity projection of multidetector-row computed tomography for assessment of pulmonary hypertension in children with congenital heart disease. |
| PubMedID- 25701970 | Introduction: vasoconstrictive endothelin signaling is not limited to idiopathic pulmonary arterial hypertension, but has also been implicated in pulmonary hypertension due to valvular heart disease. |
| PubMedID- 23241003 | Since left heart failure may be associated with pulmonary hypertension "out of proportion to left heart disease," sildenafil may have beneficial effect in such patients. |
| PubMedID- 24358351 | pulmonary hypertension due to left heart disease (group ii) and associated with chronic lung disease (group iii) are the most commonly observed ph groups in the population [16]. |
| PubMedID- 23890862 | Long-term effects of continuous prostacyclin therapy in adults with pulmonary hypertension associated with congenital heart disease. |
| PubMedID- 25705389 | Current classification describes five main groups with shared clinical and pathophysiological characteristics (figure 1): group 1, pah; group 2, pulmonary hypertension associated with left heart disease; group 3, pulmonary hypertension associated with lung disease; group 4, chronic thromboembolic pulmonary hypertension (cteph); and group 5, miscellaneous with unclear mechanisms [2]. |
| PubMedID- 23258775 | Our study aimed to determine the prevalence of occult left-heart disease in patients with scleroderma and pulmonary hypertension. |
| PubMedID- 25453535 | The diastolic pulmonary gradient does not predict survival in patients with pulmonary hypertension due to left heart disease. |
| PubMedID- 22884380 | pulmonary hypertension associated with left heart disease is the most common form of pulmonary hypertension encountered in clinical practice today. |
| PubMedID- 22748905 | pulmonary hypertension associated with left-sided heart disease. |
| PubMedID- 24361805 | Background: pulmonary hypertension due to left heart disease is very common. |
| PubMedID- 22526220 | Elevated homocysteine and asymmetric dimethyl arginine levels in pulmonary hypertension associated with congenital heart disease. |
| PubMedID- 21769595 | Perioperative management of pulmonary hypertension in children with critical heart disease. |
| PubMedID- 24561861 | Patients with pulmonary hypertension associated with congenital heart disease survive longer with preserved right ventricular (rv) function compared with those with primary pulmonary hypertension. |
| PubMedID- 25089008 | Left heart disease: a frequent cause of early pulmonary hypertension in systemic sclerosis, unrelated to elevated nt-probnp levels or overt cardiac fibrosis but associated with increased levels of mr-proanp and mr-proadm: retrospective analysis of a french canadian cohort. |
| PubMedID- 23789186 | This article gives an overview of the importance and pathophysiology of pulmonary hypertension associated with left heart disease, and discusses the challenges associated with its diagnosis and treatment. |
| PubMedID- 24019248 | We report the clinical and histological findings and discuss about the impact of this unexpected and not-previously described associated lesion on the prognosis and on the therapeutic strategy in patients with pulmonary hypertension associated with congenital heart disease. |
| PubMedID- 20459681 | 3 years old female patient, known case of congenital heart disease with pulmonary hypertension and cerebral palsy was admitted to the hospital on 7th october 2009 with high grade of fever, cough, sore throat, difficulty in breathing and body aches. |
| PubMedID- 23906950 | Group 2 comprises pulmonary hypertension owing to left heart disease; group 3, pulmonary hypertension owing to lung diseases and/or hypoxia; group 4, chronic thromboembolic pulmonary hypertension; and group 5, pulmonary hypertension of unknown cause. |
| PubMedID- 23829793 | Group 2 'pulmonary hypertension due to left heart diseases' is divided into three sub-groups: systolic dysfonction, diastolic dysfonction and valvular dysfonction. |
| PubMedID- 26504732 | The treatment of choice for pulmonary hypertension due to left heart disease (group 2), due to lung disease (group 3) or due to unclear multifactorial mechanisms (group 5) is the state-of-the-art therapy of the underlying disease. |
| PubMedID- 22494051 | Quantitative evaluation of right ventricle function by transthoracic echocardiography in childhood congenital heart disease patients with pulmonary hypertension. |
| PubMedID- 24999252 | Background: pulmonary hypertension (ph) associated with left heart disease (world health organization [who] group ii) has previously been linked with significant morbidity and mortality. |
| PubMedID- 24739042 | The current classification is based on the who-conference in nice (2013)[1] and separates the term pulmonary arterial hypertension (pah) from pulmonary hypertension (ph) due to left heart disease, pulmonary disease, chronic thromboembolic pulmonary hypertension (cteph) and ph of miscellaneous etiologies. |
| PubMedID- 24075485 | Background: pulmonary hypertension associated with congenital heart disease increases the risk of surgery using cardiopulmonary bypass. |
| PubMedID- 26262457 | Purpose of review: pulmonary hypertension associated with left heart disease is the most commonly encountered form of pulmonary hypertension and is associated with a poor prognosis. |
| PubMedID- 26559982 | Palliative senning in the treatment of congenital heart disease with severe pulmonary hypertension. |
| PubMedID- 25076997 | pulmonary hypertension (ph) due to left heart disease is the most common cause of pulmonary hypertension in the western world. |
| PubMedID- 20515628 | In patients with pulmonary hypertension due to left heart disease or lung disease, treatment focuses on the underlying condition and there is no convincing evidence that agents approved for pulmonary arterial hypertension are effective. |
| PubMedID- 25721948 | Introduction: pulmonary hypertension (ph) due to left-sided heart disease (group 2 ph) is most commonly due to passive backward transmission of elevated left-sided heart pressures. |
| PubMedID- 20494465 | Lung biopsy findings in previously inoperable patients with severe pulmonary hypertension associated with congenital heart disease. |
| PubMedID- 20646560 | [the actuarial survival analysis to the surgical and non-surgical therapy regime for congenital heart disease with severe pulmonary hypertension]. |
| PubMedID- 23592742 | pulmonary hypertension (ph) due to left heart disease is classified as group ii according to the dana point classification, which includes left ventricular systolic and/or diastolic left heart failure, and left-sided valvular disease. |
| PubMedID- 23015200 | No medical treatment has been established to ameliorate pulmonary hypertension (ph) due to left heart disease. |
| PubMedID- 23559349 | There has been no established medical therapy to ameliorate pulmonary hypertension (ph) owing to left heart disease (lhd-ph). |
| PubMedID- 24039255 | Despite the importance of pulmonary veins in normal lung physiology and the pathobiology of pulmonary hypertension with left heart disease (ph-lhd), pulmonary veins remain largely understudied. |
| PubMedID- 20924360 | pulmonary hypertension (ph) with left-sided heart disease is defined, according to the latest venice classification, as a group 2 ph, which includes left-sided ventricular or atrial disease, and left-sided valvular diseases. |
| PubMedID- 20522580 | pulmonary hypertension associated with congenital heart disease: pulmonary vascular disease: the global perspective. |
| PubMedID- 20646485 | [inhaled iloprost during acute pulmonary vasodilator testing for preoperative assessment of surgical operability of congenital heart disease with severe pulmonary hypertension]. |