PedAM
Pediatric Disease Annotations & Medicines
| Disease | heart disease |
| Phenotype | C0004153|atherosclerosis |
| Sentences | 47 |
| PubMedID- 23840954 | The uptake of large amounts of lipids from plasma lipoproteins via endocytosis by macrophages in the artery wall to form lipid-engorged foam cells is an important initiating event in the development of atherosclerosis, a major cause of heart disease. |
| PubMedID- 21334453 | atherosclerosis, the primary cause of coronary heart disease, is an inflammatory disorder orchestrated by the action of cytokines. |
| PubMedID- 22159319 | Since the use of ptca in the treatment of coronary atherosclerosis, numerous patients with coronary heart disease have benefited from pci, but the relatively high incidence of restenosis after pci has been a major problem, despite the short-term success of this technique. |
| PubMedID- 25861201 | Introduction: atherosclerosis leading to ischemic heart disease (ihd) is the most common cause of cardiac deaths worldwide. |
| PubMedID- 21343206 | atherosclerosis, the underlying cause of coronary heart disease and ischaemic stroke, is increasingly understood to be a chronic, low grade inflammatory disease of the arterial wall.4 increased levels of inflammatory markers have been associated with risk of cardiovascular disease.5 6 new studies have examined not only the effect of alcohol on lipid levels and haemostatic factors but also on other measures of inflammation and endothelial cell function as well as levels of adipocyte hormones. |
| PubMedID- 20965587 | Reduced body iron stores and atherosclerosis in patients with cyanotic congenital heart disease. |
| PubMedID- 25933642 | Even though a large number of women have obstructive atherosclerosis as a cause of ischemic heart disease, a substantial number of women do not. |
| PubMedID- 19913857 | Low folate and high homocysteine levels are emerging as important risk factors for atherosclerosis and predictors of early coronary heart disease. |
| PubMedID- 20364398 | Interleukin-4 (il-4) has important role in immune cell chemotaxis, formation of endothelial cell adhesion molecules and has numerous anti-inflammatory effects which prevent the complications of atherosclerosis, the primary cause of coronary heart disease (chd). |
| PubMedID- 26576421 | atherosclerosis, the primary cause of heart disease and stroke, is responsible for approximately 50% of all deaths in western societies and is the leading cause of deaths worldwide [1]. |
| PubMedID- 24748883 | [12],[13] reports also indicated insulin resistance is an independent predictor of atherosclerosis plaque progression in patients with coronary heart disease,[14] and the increased plasma ffas levels were an important cause of obesity-associated insulin resistance. |
| PubMedID- 22709409 | Insulin resistance is an independent predictor of atherosclerosis plaque progression in patients with coronary heart disease in both the diabetic and non-diabetic population. |
| PubMedID- 20503072 | Pylori) strains infection on coronary atherosclerosis in patients with coronary heart disease and to elucidate how cytotoxin-associated gene a (caga)-positive h. |
| PubMedID- 23936087 | The risk of atherosclerosis, a major cause of coronary heart disease (chd) is inversely proportional to high density lipoprotein (hdl) cholesterol [1], [2]. |
| PubMedID- 21942962 | [prevalence and clinical significance of multifocal atherosclerosis in patients with ischemic heart disease]. |
| PubMedID- 20526039 | atherosclerosis in patients with cyanotic congenital heart disease. |
| PubMedID- 22695460 | Lipid disorders (e.g., high blood cholesterol and triglycerides) increase the risk for atherosclerosis, which can lead to coronary heart disease (chd), which accounts for a substantial proportion of cardiovascular mortality. |
| PubMedID- 21821058 | Depressive symptoms have been consistently associated with sub-clinical atherosclerosis and future risk of coronary heart disease events. |
| PubMedID- 23590337 | Ir was also seen to be an independent predictor of atherosclerosis plaque progression in patients with coronary heart disease in both the diabetic and non-diabetic population [20]. |
| PubMedID- 22291840 | A 74-year-old male with generalized atherosclerosis being the cause of ischaemic heart disease, abdominal aortic and right common iliac artery aneurysm, subacute ischaemia of the left leg with dry necrosis of the 5th toe of the left foot, and also with renal failure, arterial hypertension and permanent atrial fibrillation, was hospitalised due to acute coronary syndrome with additional troponin values. |
| PubMedID- 23237394 | [effect of type 2 diabetes mellitus on extent of multifocal atherosclerosis in patients with ischemic heart disease]. |
| PubMedID- 22956783 | atherosclerosis, the foremost cause of coronary heart disease, is a multifactorial andmultistep disease. |
| PubMedID- 26328503 | Coronary heart disease because of atherosclerosis is still the most common cause of mortality. |
| PubMedID- 24167546 | It has been shown that atherosclerosis, the underlying cause of coronary heart disease, can occur even in children and adolescents [1]–[3]. |
| PubMedID- 23119182 | Because of these abnormalities, it is thought that rheumatologic disorders have been associated with premature atherosclerosis leading to ischemic heart disease at young ages. |
| PubMedID- 23536941 | Aim: to study the spread of a number of indicators of subclinical atherosclerosis in patients with coronary heart disease (chd) and the pattern of their relationship to their functional state and muscle mass. |
| PubMedID- 21157110 | Background: coronary artery calcification (cac) scores are widely accepted to predict risk of coronary heart diseases and are associated with atherosclerosis in other vasculatures. |
| PubMedID- 21490774 | Epidemiological studies have revealed that higher levels of hdl cholesterol in blood are associated with protection and that lower levels of hdl cholesterol in blood are associated with increased risk for atherosclerosis leading to heart disease [15]. |
| PubMedID- 25415545 | atherosclerosis, the root cause of ischemic heart disease, is promoted by risk factors like elevated plasma low-density lipoprotein, low plasma high-density lipoprotein, smoking, hypertension, and diabetes mellitus. |
| PubMedID- 25944976 | Systemic inflammation plays a major role in the development of atherosclerosis leading to coronary heart disease. |
| PubMedID- 22368751 | Discussions for day two included atherosclerosis, investigation of ischaemic heart disease, the acute coronary syndrome, acute myocardial infarction and antiplatelet therapy. |
| PubMedID- 25231173 | They have severe atherosclerosis and die of ischemic heart disease usually in theirthird decade of life. |
| PubMedID- 20857186 | Patients were made aware that cac identifies underlying coronary atherosclerosis and is associated with incident heart disease. |
| PubMedID- 22725704 | Hypercholesterolemia plays a key role in the development and progression of atherosclerosis and can lead to cardiac heart disease. |
| PubMedID- 20591344 | Advanced atherosclerosis, through thrombosis, leads to ischemic heart disease and ischemic stroke, the leading causes of death and disability worldwide. |
| PubMedID- 20937081 | It has been noted that zinc deficiency is associated with atherosclerosis and development of ischemic heart diseases, and zinc supplementation is used to help treat angina pectoris [70]. |
| PubMedID- 22489713 | Tac determination through a modified trap assay has been reported as a useful ex vivo biomarker for atherosclerosis staging in patients with coronary heart disease [99]. |
| PubMedID- 23637837 | High levels of apob can lead to plaques that cause vascular disease (atherosclerosis), leading to heart disease [18]. |
| PubMedID- 22413998 | Hyperlipidemia, also known as hyperlipoproteinemia or high cholesterol, is caused by abnormal lipid and lipoprotein metabolism, which is a disorder characterized by abnormally high concentration of lipids (fats) in the blood that are correlated with the development of atherosclerosis, the underlying cause of coronary heart disease (chd) and stroke [1]. |
| PubMedID- 21533112 | Ischemic heart disease resulting from coronary atherosclerosis is the leading cause of human mortality worldwide [1], [2]. |
| PubMedID- 25842659 | Conclusion: specific features of the cardiovascular pathology and a course of coronary heart disease in combination with atherosclerosis of the abdominal aorta and its visceral branches are revealed. |
| PubMedID- 21649590 | Purpose: to assess effects of niacin on risk factors of atherosclerosis in men with coronary heart disease (chd) and high lipoprotein(a) [lp(a)] levels. |
| PubMedID- 21473966 | Women have less severe and extensive coronary atherosclerosis in fatal cases of ischemic heart disease: an autopsy study. |
| PubMedID- 23953044 | Aim of the study was to assess prognostic role of high sensitivity c-reactive protein (crp) in progression of atherosclerosis in patients with ischemic heart disease (ihd) in a year after coronary artery bypass grafting (cabg). |
| PubMedID- 21633059 | By the 1950s and 1960s, research had associated atherosclerosis with heart disease and established that artery-clogging plaques were composed largely of cholesterol. |
| PubMedID- 26047327 | Childhood obesity can adversely affect many organ systems and often cause serious consequences, including hypertension, dyslipidemia, diabetes, atherosclerosis and increased incidence of coronary heart disease in later life[3–5]. |
| PubMedID- 20665290 | This study demonstrated that cloned, genetically-defined apoe4 pigs provided balanced nutrition diets provide an experimental system ideally suited to examining atherosclerosis and the onset of coronary heart disease. |
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