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PedAM

Pediatric Disease Annotations & Medicines




Disease graft-vs-host disease
Phenotype C0026946|fungal infection
Sentences 5
PubMedID- 21200413 The patient's posttransplant course was complicated by hepatic fungal infections, gvhd, involving the upper gastrointestinal tract and liver, and renal insufficiency resulting in a very slow but physically remarkable recovery to eventually include triathlon training.
PubMedID- 22215361 Purpose: the results of a pharmacoeconomic study of the cost-effectiveness of posaconazole versus fluconazole in preventing invasive fungal infections (ifis) in patients with graft-versus-host disease (gvhd) are reported.
PubMedID- 21694893 Another international study by ullmann et al in 2007 looked at prophylaxis against invasive fungal infections in patients with graft-versus-host disease (gvhd) on immunosuppressive treatment and compared posaconazole with fluconazole.24 this was a randomized, double-blind trial including patients who received an allogeneic hematopoietic stem cell transplant and developed gvhd.
PubMedID- 19802030 Economic evaluation of posaconazole vs fluconazole in the prevention of invasive fungal infections in patients with gvhd following haematopoietic sct.
PubMedID- 21716917 A recent large-scale study reported that an average of 112-day prophylactic posaconazole therapy effectively prevented invasive fungal infection in patients with gvhd [94].

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