PedAM
Pediatric Disease Annotations & Medicines
| Disease | graft-vs-host disease |
| Phenotype | C0023418|leukaemia |
| Sentences | 3 |
| PubMedID- 23873335 | Several therapies that are effective in preventing gvhd usually lead to reduced graft-versus-leukaemia activity (gvl), which is the ability of donor-derived infused lymphocytes in a haematopoietic stem cell-transplanted patient to react against leukemic cells, invalidating their effective applications [50,51,52,53]. |
| PubMedID- 23180793 | In 2008, a tool was added to the website to help predict nk cell alloreactivity based on the kir ligands present in the patient and donor, as transplant strategies based on kir-ligand mismatches had been shown to influence relapse, graft versus host disease and survival in patients with acute myeloid leukaemia (33). |
| PubMedID- 24112249 | Introduction: to further define the relative impact of immunotherapy and subsequent development of graft-versus-host disease (gvhd) on survival in patients with relapsed acute leukaemia postallogeneic hematopoietic stem cell transplant (sct), we performed a single-centre retrospective analysis of 32 actively treated patients between 2003 and 2011. |
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