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PedAM

Pediatric Disease Annotations & Medicines




Disease gout
Phenotype C0042373|vascular diseases
Sentences 3
PubMedID- 25594854 The mechanisms that link high serum uric acid levels and gout with cardiovascular diseases are multifactorial, implicating low-grade systemic inflammation and xanthine oxidase activity as well as the deleterious effect of hyperuricaemia itself.
PubMedID- 22676161 Given the recent dramatic increase in the incidence of gout and hyperuricemia associated with cardiovascular diseases and metabolic syndrome [13], it is highly desirable to introduce a safe and economic way to reverse these trends.
PubMedID- 21886828 High serum uric acid (sua) levels can lead to gout and is associated with cardiovascular diseases and diabetes [1], whereas low sua levels may be associated with multiple sclerosis [2], [3].

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