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PedAM

Pediatric Disease Annotations & Medicines




Disease gout
Phenotype C0007222|cardiovascular disease
Sentences 8
PubMedID- 25165032 Since there is evidence that cardiovascular disease in patients with gout often goes unrecognised and undertreated in primary care, with only a quarter of people consulting with acute gout screened for cardiovascular risk factors within the subsequent month,43 despite both national and international guidance recommending this,44–46 the results of this study suggest a substantial need to change practice.
PubMedID- 26504360 Therefore, gout is positively associated with cardiovascular disease risk and mortality.
PubMedID- 25399391 Conclusion: the direct and indirect costs-of-illness of gout are primarily associated with cardiovascular disease, functional limitations, and female sex.
PubMedID- 22676161 Given the recent dramatic increase in the incidence of gout and hyperuricemia associated with cardiovascular diseases and metabolic syndrome [13], it is highly desirable to introduce a safe and economic way to reverse these trends.
PubMedID- 25594854 The mechanisms that link high serum uric acid levels and gout with cardiovascular diseases are multifactorial, implicating low-grade systemic inflammation and xanthine oxidase activity as well as the deleterious effect of hyperuricaemia itself.
PubMedID- 26515421 Despite the increasing evidence that both hyperuricemia and gout are associated with cardiovascular disease, no studies have, to our knowledge, attempted to address whether msu precipitation confers a particular risk of cardiovascular disease above what is already inherent in having hyperuricemia.
PubMedID- 21886828 High serum uric acid (sua) levels can lead to gout and is associated with cardiovascular diseases and diabetes [1], whereas low sua levels may be associated with multiple sclerosis [2], [3].
PubMedID- 23533601 The association of gout with cardiovascular disease, first described in the 19th century was thought to be an association, rather than a cause, of cardiovascular disease.

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