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PedAM

Pediatric Disease Annotations & Medicines




Disease glucose intolerance
Phenotype C0020538|hypertension
Sentences 2
PubMedID- 24125845 Recent clinical studies show that rd significantly attenuates muscle sympathetic nerve activity42 and improves cardiac hypertrophy and function,10 atrial fibrillation,11 glucose intolerance43 in patients with resistant hypertension, thereby supporting the concept that rd can have the benefit in prevention of cardiovascular injury through afferent renal nerve ablation.
PubMedID- 21709286 hypertension is characteristically associated with glucose intolerance, with hyperinsulinemia, and with roughly a 50% reduction in insulin sensitivity, unaffected by antihypertensive treatment; reaven reviewed a study of both treated and untreated hypertensive individuals, showing that 34 and 39%, respectively, had intermediate and that 52 and 47% had low insulin sensitivity, with the minority being insulin sensitive.

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