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PedAM

Pediatric Disease Annotations & Medicines




Disease glucose intolerance
Phenotype C0011860|type 2 diabetes
Sentences 11
PubMedID- 22936178 Downregulation of glut4 expression in skm is a major mechanism, which contributes to glucose intolerance associated with type 2 diabetes (31).
PubMedID- 20862330 Dysregulated branched-chain metabolism may make an independent contribution to development of insulin resistance and glucose intolerance, ultimately leading to type 2 diabetes [25].
PubMedID- 23570346 In previous studies we showed that in japanese-brazilians, low plasma level of total adiponectin is an independent predictor of glucose intolerance and subjects with type 2 diabetes compared with normal glucose tolerant subjects have reduced levels of total adiponectin [14,20].
PubMedID- 23573479 Male kk/ta mice spontaneously exhibit type 2 diabetes associated with hyperglycemia, glucose intolerance, hyperinsulinemia, mild obesity and microalbuminuria, conditions which are more severe than those found in the female (2-4).
PubMedID- 20879973 We aimed to systematically identify and evaluate those studies that have investigated the impact of lifestyle interventions on the prevention of the development of incident type 2 diabetes in those with glucose intolerance.
PubMedID- 21818460 Combination of weight loss and exercise to reduce the incidence of type 2 diabetes in patients with glucose intolerance should not be dismissed [5,6].
PubMedID- 21926287 Objective the increased risk of type 2 diabetes in women with glucose intolerance in pregnancy is mediated by deterioration of their beta-cell function, which occurs as early as the first year postpartum.
PubMedID- 25898207 Insulin resistance and islet β-cell dysfunction are important in the pathogenesis of glucose intolerance leading to type 2 diabetes [37].
PubMedID- 23319937 Thus, l-pgds is an important mediator of muscle and adipose glucose transport which is modulated by glycemic conditions and plays a significant role in the glucose intolerance associated with type 2 diabetes [69].
PubMedID- 20831945 Recombinant mup1 markedly ameliorates hyperglycemia and glucose intolerance in mice with type 2 diabetes.
PubMedID- 21574956 Aging affects energy homeostasis and fuel metabolism in a form of either an increased body mass and glucose intolerance that may lead to obesity and type 2 diabetes or loss of appetite that also may seriously compromise health status.

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