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PedAM

Pediatric Disease Annotations & Medicines




Disease glomerulosclerosis
Phenotype C0020538|hypertension
Sentences 8
PubMedID- 25622251 Dn is often associated with hypertension and symptoms of dn are albuminuria, glomerulosclerosis and interstitial kidney fibrosis.
PubMedID- 25034792 Endothelial nitric oxide synthase deficiency (enos(-/-)) results in moderate hypertension and the development of nodular glomerulosclerosis and hyaline arteriosclerosis in streptozotocin-induced diabetic c57bl/6j mice.
PubMedID- 23110194 This may be explained by the fact that in animal studies, chronic no synthase inhibition causes systemic and glomerular hypertension with consecutive glomerulosclerosis, tubulointerstitial injury, and proteinuria [11].
PubMedID- 21660521 Evidence for this mechanism was found in different rat models of focal and segmental glomerulosclerosis with or without hypertension [7, 21, 22].
PubMedID- 20576153 Our patient's past medical history was significant for focal segmental glomerulosclerosis leading to esrd, hypertension, a seizure disorder, anemia of chronic disease, and shpt.
PubMedID- 20051853 Recent findings: the nonmuscle myosin heavy chain 9 gene (myh9) is associated with a spectrum of kidney diseases in african americans, including idiopathic focal global glomerulosclerosis historically attributed to hypertension, idiopathic focal segmental glomerulosclerosis, and the collapsing variant of focal segmental glomerulosclerosis [hiv-associated nephropathy (hivan)].
PubMedID- 25775254 Salt-loaded dss rats developed severe hypertension, proteinuria, glomerulosclerosis, and elevation of serum creatinine level in 6 weeks of hs diet [31].
PubMedID- 25755650 Podocyte hypertrophy occurs with glomerular capillary hypertension ultimately leading to progressive glomerulosclerosis (83).

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