PedAM
Pediatric Disease Annotations & Medicines
| Disease | glomerulosclerosis |
| Phenotype | C0011881|diabetic nephropathy |
| Sentences | 7 |
| PubMedID- 20450059 | The pathomechanisms of glomerulosclerosis in diabetic nephropathy (dn) are considered to be related with glycometabolism disorder, podocyte injury, intra-renal hemodynamics abnormality, fibrogenic cytokines over-expression, oxidative stress and inflammatory reaction. |
| PubMedID- 23552865 | Osteopontin (opn) expression has been reported to be elevated in experimental models of renal injury such as arterial hypertension or diabetic nephropathy finally leading to focal segmental glomerulosclerosis (fsgs). |
| PubMedID- 25318553 | In the histopathological investigation there was severe glomerulosclerosis in patients with diabetic nephropathy, but the responders were noticeable in that they only had mild tubulointerstitial damage. |
| PubMedID- 20146476 | Therefore, isoliquiritigenin may be a potential therapeutic agent for the prevention and treatment of mesangial fibrosis and glomerulosclerosis leading to diabetic nephropathy due to longstanding diabetes mellitus. |
| PubMedID- 21905281 | Renal histopathology of these animals showed features of diabetic nephropathy, with nodular glomerulosclerosis and vacuolation of proximal tubule cells (armanni-ebstein phenomenon). |
| PubMedID- 25954204 | Hrp has been shown to prevent glomerulosclerosis in diabetic nephropathy (ichihara et al., 2004). |
| PubMedID- 22285932 | diabetic nephropathy is associated with glomerular hypertrophy, glomerulosclerosis, tubulointerstitial fibrosis, mesangial cell expansion, followed by albuminuria and reduction in glomerular filtration rate. |
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