PedAM
Pediatric Disease Annotations & Medicines
| Disease | glomerulosclerosis |
| Phenotype | C0011860|type 2 diabetes |
| Sentences | 3 |
| PubMedID- 20067909 | Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone h3k9 and h3k23 acetylation, h3k4 dimethylation and phosphorylation at serine 10. |
| PubMedID- 21703397 | Monocyte/ chemoattractant protein-1/chemokine ligand (ccl) 2 and stromal cell-derived factor-1/cxcl12 both contribute to glomerulosclerosis in mice with type 2 diabetes mellitus, through different mechanisms. |
| PubMedID- 24195695 | Thus high doses of valsartan not only reduce albuminuria maximally, but also halt the progression of the glomerulosclerosis resulting from type 2 diabetes via a reduction in podocyte injury and renal oxidative stress and inflammation. |
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