PedAM
Pediatric Disease Annotations & Medicines
| Disease | gastroesophageal reflux disease |
| Phenotype | C0037317|sleep disturbances |
| Sentences | 8 |
| PubMedID- 23119069 | Another potential mechanism is that medications used for sleep disturbances might provoke or aggravate gerd [22]. |
| PubMedID- 21752736 | sleep disturbances associated with gastro-oesophageal reflux disease: prevalence and impact of treatment in french primary care patients. |
| PubMedID- 23611985 | A total of 22,826 ppi users (87.94%) reported having heartburn or regurgitation, sleep disturbances due to gerd symptoms, or intake of over-the-counter acid suppressive medication for more than 1 day per week. |
| PubMedID- 24008338 | sleep disturbances were significantly associated with refractory gerd symptoms. |
| PubMedID- 22592763 | Clinical evidence strongly suggests that gerd is associated with sleep disturbances such as shorter sleep duration, difficulty falling asleep, arousals during sleep, poor sleep quality, and awakening early in the morning. |
| PubMedID- 25604848 | gastroesophageal reflux disease (gerd) is strongly associated with sleep disturbances. |
| PubMedID- 25786444 | Objective: gastroesophageal reflux disease (gerd) is strongly associated with sleep disturbances. |
| PubMedID- 20535322 | Several studies have evaluated the efficacy of ppi therapy for sleep disturbances in patients with gerd but few randomized blinded placebo controlled clinical trials are available (table 3).47-50 johnson and colleagues47 performed a large multicenter randomized double-blind placebo-controlled trial utilizing esomeprazole 40 mg, 20 mg, or placebo for 6 weeks in 675 adults with gerd-associated sleep disturbance. |
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