PedAM
Pediatric Disease Annotations & Medicines
| Disease | gastroesophageal reflux disease |
| Phenotype | C0037317|sleep disturbance |
| Sentences | 15 |
| PubMedID- 24426606 | We describe the case of a 38-year-old male patient with a history of sleep disturbance attributable to gastroesophageal reflux disease, which resolved on successful laparoscopic nissen fundoplication treatment. |
| PubMedID- 21752736 | sleep disturbances associated with gastro-oesophageal reflux disease: prevalence and impact of treatment in french primary care patients. |
| PubMedID- 21418126 | Eighty-four percent of patients reported sleep disturbance attributable to nighttime reflux, including typical nighttime supine reflux symptoms (72%), difficulties to fall asleep (39%), waking up during the night (45%), morning fatigue (35%), and reflux symptoms when waking up in the morning (47%). |
| PubMedID- 23611985 | A total of 22,826 ppi users (87.94%) reported having heartburn or regurgitation, sleep disturbances due to gerd symptoms, or intake of over-the-counter acid suppressive medication for more than 1 day per week. |
| PubMedID- 22592763 | Clinical evidence strongly suggests that gerd is associated with sleep disturbances such as shorter sleep duration, difficulty falling asleep, arousals during sleep, poor sleep quality, and awakening early in the morning. |
| PubMedID- 24765533 | The gerdq questionnaire is composed of 4 positive predictors of gerd (heartburn, regurgitation, sleep disturbance due to reflux symptoms, and the use of over-the-counter medication; questions 1, 2, 5, and 6, respectively), and 2 negative correlates with gerd (epigastric pain and nausea; questions 3 and 4, respectively).14,19 the gerdq scores were based on the frequency of 6 items during the past 7 days ranging from 0 to 3 for the positive predictors, and from 3 to 0 (in reversed order, with 3 representing 'none') for negative predictors. |
| PubMedID- 23350049 | Interestingly, the prevalence of sleep disturbance due to gerd symptoms at least once per week was higher in the nerd (23.5%) and fh (16.7%) than in the ee (12.9%) but without statistical significance in the present study. |
| PubMedID- 24714269 | The aim of this pilot study was to quantify nocturnal acid and nonacid reflux in patients with previously diagnosed sleep disturbance. |
| PubMedID- 23119069 | One model suggests a vicious circle, i.e., that sleep disturbances provoke reflux, which in turn worsens sleep problems, which in turn worsen gerd [24]. |
| PubMedID- 23432146 | Conclusion: a pass strategy identifies gerd patients with sleep disturbance in primary care that will benefit from a change in acid-suppressive therapy. |
| PubMedID- 25786444 | Objective: gastroesophageal reflux disease (gerd) is strongly associated with sleep disturbances. |
| PubMedID- 24008338 | sleep disturbances were significantly associated with refractory gerd symptoms. |
| PubMedID- 25604848 | gastroesophageal reflux disease (gerd) is strongly associated with sleep disturbances. |
| PubMedID- 20535322 | Nighttime reflux can lead to sleep disturbance and sleep disturbance may further aggravate gerd by prolonged acid contact time and heightened sensory perception. |
| PubMedID- 24450939 | As shown in table 4, factors associated with reporting ts were frequency of acid regurgitation, epigastric pain/burning (probably reflecting related dyspepsia), and sleep disturbance due to reflux symptoms. |
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