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PedAM

Pediatric Disease Annotations & Medicines




Disease gastroesophageal reflux disease
Phenotype C0017168|gastro-oesophageal reflux
Sentences 5
PubMedID- 21459504 The previous paradigm of airway reflux as synonymous with the classic gastro-oesophageal reflux disease (gord) causing heartburn has been overturned.
PubMedID- 23721547 Background: arbaclofen placarbil is a pro-drug of the gamma-aminobutyric acid-b agonist r-baclofen that has been shown to reduce reflux episodes in patients with gastro-oesophageal reflux disease (gerd).
PubMedID- 24759350 Its principle is similar to the controlled delivery of rf energy to the lower oesophageal sphincter region (the stretta procedure), which was proposed as an alternative to standard anti-reflux surgery in patients with gastro-oesophageal reflux disease.
PubMedID- 21320138 Randomised clinical trial: effects of monotherapy with adx10059, a mglur5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease.
PubMedID- 21402616 Objective: o evaluate the efficacy and tolerability of add-on treatment with lesogaberan (azd3355), a novel reflux inhibitor, in patients with persistent gastro-oesophageal reflux disease (gord) symptoms despite proton pump inhibitor (ppi) therapy.

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