PedAM
Pediatric Disease Annotations & Medicines
| Disease | gastric cancer |
| Phenotype | C0278701|gastric adenocarcinoma |
| Sentences | 3 |
| PubMedID- 22826628 | Methods: from january 2001 to december 2006, 487 patients with histologically confirmed primary gastric adenocarcinoma were diagnosed with stage ii gastric cancer according to the new 7th edition american joint committee on cancer stage classification at the department of gastric cancer and soft tissue surgery, fudan university shanghai cancer center. |
| PubMedID- 24518125 | In gastric cancer patients associated with pga, gastric adenocarcinoma and adjacent pga were separately evaluated, and both lesions had lost mlh1/pms2 expression in patients #1 and #14 and msh2/msh6 expression in patient #8. in 14 sporadic pgas, there were no losses of mismatch-repair proteins in any of the cases. |
| PubMedID- 23058008 | In conclusion, yap is strongly expressed in gastric adenocarcinomas, and knockdown of yap may inhibit gastric cancer cell proliferation and metastasis through down-regulation of pcna and mmp-2 expression, suggesting that yap represents an important therapeutic target in human gastric cancer. |
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