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PedAM

Pediatric Disease Annotations & Medicines




Disease gastric cancer
Phenotype C0006625|cachexia
Sentences 6
PubMedID- 21223691 Objective: to investigate whether the single nucleotide polymorphisms (snps) at -1082, -819 and -592 of interleukin-10 gene and its haplotype are associated with cachexia in patients with gastric cancer.
PubMedID- 20421626 Our results suggest that genetic polymorphisms of il-10 contribute to the susceptibility to cachexia in patients with gastric cancer in the chinese population.
PubMedID- 20359252 Interleukin-10 gene polymorphisms influence susceptibility to cachexia in patients with low-third gastric cancer in a chinese population.
PubMedID- 24720758 The altered tight junctions: an important gateway of bacterial translocation in cachexia patients with advanced gastric cancer.
PubMedID- 19929572 To test this hypothesis, we investigated the potential influence of the polymorphisms of the il-8 gene, -251 a/t and +781 c/t, on susceptibility to cachexia from patients with gastric cancer in a chinese population, using polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp).
PubMedID- 24404136 It is currently not entirely clear which type of fibres are affected in human cancer cachexia, however, in patients with oesophago-gastric cancer cachexia early loss of all myhc isoforms has been reported [4].

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