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PedAM

Pediatric Disease Annotations & Medicines




Disease focal segmental glomerulosclerosis
Phenotype C0022658|nephropathy
Sentences 6
PubMedID- 23908849 It includes: 1) hiv-associated nephropathy (hivan), a form of focal segmental glomerulosclerosis that is accompanied by tubuleinterstitial inflammation, and clinically manifests as rapidly progressive renal failure with nephritic range proteinuria.
PubMedID- 21279725 Here we report the use of rituximab in four children with idiopathic steroid-resistant nephrotic syndrome (srns) with various histological backgrounds (two cases with focal segmental glomerulosclerosis, one case with igm nephropathy, and one case with minimal change disease), who failed to respond to other immunsuppressions.
PubMedID- 20051853 Genetic analyses in patients with essential hypertension and nephropathy attributed to hypertension, focal segmental glomerulosclerosis and hivan reveal that myh9 gene polymorphisms are associated with a spectrum of kidney diseases in this ethnic group.
PubMedID- 23552865 Osteopontin (opn) expression has been reported to be elevated in experimental models of renal injury such as arterial hypertension or diabetic nephropathy finally leading to focal segmental glomerulosclerosis (fsgs).
PubMedID- 22282598 In addition to the classic hiv-1-associated nephropathy with collapsing-type focal segmental glomerulosclerosis and characteristic tubulocystic changes, which is more common in afro-american than in caucasian hiv-1 patients, immune complex gns such as membranous gn and membranoproliferative gn are particularly common renal manifestations.
PubMedID- 22844593 Podocytopathies (minimal change disease (mcd) and focal segmental glomerulosclerosis (fsgs)) together with membranous nephropathy are the main causes of nephrotic syndrome.

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