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PedAM

Pediatric Disease Annotations & Medicines




Disease esophageal cancer
Phenotype C0007137|squamous cell carcinoma
Sentences 7
PubMedID- 23128894 Treatment strategy for superficial pharyngeal squamous cell carcinoma synchronously combined with esophageal cancer.
PubMedID- 26426606 esophageal cancer, including squamous cell carcinoma (scc) and esophageal adenocarcinoma (eac), is a serious malignancy with a poor prognosis in the majority of cases.1,2 scc is the predominant form of esophageal carcinoma worldwide, but a shift in epidemiology has been seen in some countries and regions like australia, uk, usa, and western europe, where the incidence of eac has exceeded that of scc.3 every year, >450,000 people worldwide are diagnosed with esophageal cancer and the incidence is rapidly increasing.3,4 it is the eighth most common cancer, and the sixth most common cause of cancer-related deaths worldwide with developing nations making up >80% of total cases and deaths.5,6 the mortality from these cancers is high and the response to treatments during advanced stages is poor, so effectively reducing the chances of exposure to relative risk factors will have an important impact on the incidence of esophageal cancer.
PubMedID- 22710677 In men, around 40% of oesophageal cancers are adenocarcinomas, with squamous cell carcinomas accounting for ∼20% of cases; this pattern is reversed in women (20% adenocarcinomas and 40% squamous cell carcinomas).
PubMedID- 23989943 esophageal cancer is frequently associated with squamous cell carcinoma in the head and neck.
PubMedID- 26369262 Endoscopic biopsy led to diagnosis of esophageal cancer concomitant with adenocarcinoma and squamous cell carcinoma.
PubMedID- 20716340 Hnrnp a2/b1 over-expression is not unique to lung cancer, as it has been also recorded in squamous cell carcinomas of oral and esophageal cancers [25], pancreatic cancer [31] and in cell lines established from human liver, colon and stomach cancers [23].
PubMedID- 23241138 In this model, esophageal cancer patients with squamous cell carcinoma on histology were excluded.

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