PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Phenotype | C0238111|lennox-gastaut syndrome |
| Sentences | 7 |
| PubMedID- 23471536 | Opinion statement: lennox-gastaut syndrome (lgs) is one of the most difficult epilepsy syndromes to treat, and many children are refractory to standard treatment regimens. |
| PubMedID- 20798865 | Besides its clinical use as an anticonvulsant and mood-stabilizing drug [9], vpa presents beneficial effects in clinical depression [10], absence seizures [11, 12], tonic-clonic seizures, complex partial seizures [13], juvenile myoclonic epilepsy [14], seizures associated with lennox-gastaut syndrome [15], migraine headaches, and schizophrenia. |
| PubMedID- 23827423 | Hypothalamic hamartomas cause refractory epilepsy often consistent with lennox-gastaut syndrome. |
| PubMedID- 22467791 | Eight (50%) patients had generalized epilepsy including 4 with lennox-gastaut syndrome. |
| PubMedID- 25783594 | *one australian patient evolved from a gge to a focal epilepsy.other includes lennox-gastaut syndrome, epilepsy due to tuberous sclerosis, epilepsy with electrical status epilepticus in sleep and epilepsies otherwise unclassified: none of these particular cases had unique chd2 variants. |
| PubMedID- 25847334 | Retention rates of rufinamide in pediatric epilepsy patients with and without lennox-gastaut syndrome. |
| PubMedID- 20158289 | lennox-gastaut syndrome occurs in 3% of children with epilepsy and is characterized by multiple seizure types, slow spike-and-wave discharges and a poor prognosis for seizure control and cognitive development. |
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