PedAM
Pediatric Disease Annotations & Medicines
| Disease | eosinophilia |
| Phenotype | C0004096|asthma |
| Sentences | 27 |
| PubMedID- 23134444 | By logistic regression analysis, allergic asthma, presence of peripheral eosinophilia and use of inhaled steroids remained significant. |
| PubMedID- 24991461 | Moreover, anti-ige therapy exerts profound and significant reductions in airway and tissue eosinophilia in patients with mild allergic asthma and on allergen-induced seasonal increases in circulating and tissue eosinophils in subjects with allergic rhinitis.28 these findings suggest that anti-ige therapy can be considered a steroid-sparing option for eae. |
| PubMedID- 23593249 | Beta5i-deficient mice showed reduced ova/alum- and subcutaneous/ova-induced acute asthma with decreased eosinophilia in the bronchoalveolar lavage (bal), low ova-specific igg1 and reduced local and systemic th2 cytokines. |
| PubMedID- 21505837 | [19-year-old asthma patient with pronounced eosinophilia and acute coronary syndrome]. |
| PubMedID- 25801413 | Their use as a single surrogate marker for airway eosinophilia in patients with asthma will lead to a substantial number of false positives or false negatives. |
| PubMedID- 26194544 | This study investigated the potential role of ilc2s in driving chronic airway eosinophilia in patients with severe asthma, despite regular high-dose oral corticosteroid therapy. |
| PubMedID- 22029856 | Furthermore, severe asthma exacerbations are associated with bronchial mucosal eosinophilia and neutrophilia, as well as upregulation of cxc chemoattractants and their receptors [3]. |
| PubMedID- 21320344 | Total serum ige, atopy, testing positive for food allergens, and eosinophilia were significantly associated with asthma (table 1) and evaluated as outcomes in separate statistical models. |
| PubMedID- 23253516 | Atopic asthma was associated with eosinophilia and non-atopic asthma was associated with ifn-γ and elevated monocytes in blood. |
| PubMedID- 23592945 | Churg-strauss syndrome was diagnosed based on the patient's history of asthma, sinusitis, eosinophilia, nasal polyps, transient radiological pulmonary infiltrations and transient paresthesia over the left tibia, and eosinophilic pericardial effusion and eosinophilic infiltrations revealed in a myocardial biopsy. |
| PubMedID- 22187177 | The presence of asthma, sinusitis associated with peripheral eosinophilia and organ symptoms suggesting a vasculitis could support the diagnosis, without histologic evidence. |
| PubMedID- 23091327 | Moreover, anti-ige therapy has profound and significant reducing effects on airway and tissue eosinophilia in patients with mild allergic asthma and on allergen-induced seasonal increases in circulating and tissue eosinophils in subjects with allergic rhinitis (4, 7). |
| PubMedID- 22419386 | asthma was not associated with high tissue eosinophilia (p = 0.60), with 43% of nonasthmatics demonstrating high tissue eosinophilia. |
| PubMedID- 25936567 | This suggests that ccl26 production by becs might be involved in persistent eosinophilia in patients with severe asthma despite treatment with high corticosteroid doses. |
| PubMedID- 21625544 | Allergic asthma is associated with airway eosinophilia, which is regulated by different t-effector cells. |
| PubMedID- 22541618 | In patients with severe, refractory asthma associated with eosinophilia, however, clinical trials have demonstrated significant reductions in asthma exacerbations. |
| PubMedID- 23715171 | Investigating the association of skin test reactivity, total serum ige levels, and peripheral blood eosinophilia with asthma, khadadah et al. |
| PubMedID- 23184213 | Sputum eosinophilia is associated with difficult-to-control asthma (68), and the normalization of this condition after treatment was correlated with a decrease in the number of exacerbations and hospitalizations. |
| PubMedID- 22315625 | Subsequent trials of mepolizumab in severe asthma patients with persistent sputum eosinophilia have demonstrated a significant reduction in airway wall thickness measured by quantitative ct scanning (rb1 wa%/body surface area). |
| PubMedID- 26502193 | Hmabs targeting il-5 have shown great promise in severe refractory asthma with a persisting eosinophilia, and clinical trials with hmabs against il-13 and il4ralpha have also shown clinical benefit. |
| PubMedID- 24530234 | asthma is severe, associated with eosinophilia and extrapulmonary symptoms. |
| PubMedID- 22921086 | asthma is sever, associated with eosinophilia and extrapulmonary symptoms. |
| PubMedID- 22291829 | It is well known that ics decrease airway eosinophilia, which usually leads to better asthma control, while in contrast asthma exacerbation leads to a rise in eosinophil level. |
| PubMedID- 22880030 | An ovine orthologue, galectin-14, has been shown to be secreted in the airway mucus of a sheep asthma model closely associated with lung eosinophilia [18], [25]. |
| PubMedID- 23738037 | Tarc is a pivotal chemokine for the development of th2-dominated experimental allergen-induced asthma with eosinophilia and airway hyperresponsiveness [54]. |
| PubMedID- 25981191 | Methods: we conducted a randomized, double-blind, placebo-controlled, multicenter clinical trial of sb010 involving patients who had allergic asthma with sputum eosinophilia and who also had biphasic early and late asthmatic responses after laboratory-based allergen provocation. |
| PubMedID- 26131418 | In addition to asthma, other causes of eosinophilia such as other allergic diseases, underlying cancer, and other parasitic infections should also be ruled out for the evaluation of eosinophilia. |
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