PedAM
Pediatric Disease Annotations & Medicines
| Disease | encephalopathy |
| Phenotype | C0023890|cirrhosis |
| Sentences | 55 |
| PubMedID- 20482828 | Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin ii receptor blocker combination therapy: a case report. |
| PubMedID- 23133760 | Type c he describes encephalopathy associated with cirrhosis and portal hypertension or portal-systemic shunts. |
| PubMedID- 25420513 | Long term results of balloon-occluded retrograde transvenous obliteration for portosystemic shunt encephalopathy in patients with liver cirrhosis and portal hypertension. |
| PubMedID- 25500314 | Identification of minimal hepatic encephalopathy in patients with cirrhosis based on white matter imaging and bayesian data mining. |
| PubMedID- 23111819 | The presence of portal hypertension and cirrhosis with encephalopathy could be poor prognostic factors for patients undergoing hae, especially if they are further complicated by pulmonary hypertension and cardiac failure. |
| PubMedID- 21160996 | A 66-year-old female with cryptogenic cirrhosis complicated by ascites, hepatic encephalopathy, variceal bleeding and malnutrition with meld of 34 underwent orthotopic deceased donor liver transplantation performed with piggyback technique. |
| PubMedID- 20852922 | The mean cff was higher in patients after liver transplantation, but did not reach statistical significance.table 2surrogate markers for hepatic encephalopathy in patients with liver cirrhosis and those who have received liver transplants. |
| PubMedID- 22727021 | The most widely accepted definition of alf includes evidence of coagulation abnormality, usually an inr ≥ 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of <26 weeks duration [1]. |
| PubMedID- 21978390 | Systemic translocation of gut-derived bacteria and their products is a risk factor for recurrent spontaneous bacterial peritonitis and/or encephalopathy in patients with liver cirrhosis [1,2]. |
| PubMedID- 25755452 | Inhibitory control test for the detection of minimal hepatic encephalopathy in patients with cirrhosis of liver. |
| PubMedID- 21897555 | We describe a case of an hbv-associated decompensated cirrhosis of liver with hepatic encephalopathy who developed cryptococcal pleural effusion and cryptococcal yeasts were demonstrated microscopically in stained smears of pleural fluid. |
| PubMedID- 19903725 | Standardized nomenclature has been proposed but a standardized approach to the treatment, particularly of persistent, episodic and recurrent encephalopathy associated with liver cirrhosis has not been proposed. |
| PubMedID- 25316890 | This case highlights the importance of keeping direct portopulmonary venous anastomosis in the differential diagnosis of oxygen-refractory hypoxemia and recurrent hepatic encephalopathy in patients with cirrhosis in the appropriate clinical context. |
| PubMedID- 24709242 | Objective: to determine the efficacy of rifaximin in prevention of repeated episodes of hepatic encephalopathy in patients with liver cirrhosis as compared to placebo. |
| PubMedID- 21480337 | Recent studies using anti-inflammatory agents such as ibuprofen and indomethacin have shown promise for the treatment of mild encephalopathy in patients with cirrhosis, whereas treatment with minocycline, a potent inhibitor of microglial activation, attenuates the encephalopathy grade and prevents brain edema in experimental acute liver failure. |
| PubMedID- 25374704 | He had cirrhosis which was complicated by hepatic encephalopathy and portal hypertension including bleeding esophageal varices and ascites. |
| PubMedID- 25867912 | Objective: to determine the efficacy of rifaximin once a day dose in the prevention of hepatic encephalopathy (he) in patients with liver cirrhosis as compared with twice daily dose of rifaximin. |
| PubMedID- 20508990 | Diagnosis and prognostic significance of minimal hepatic encephalopathy in patients with cirrhosis of liver. |
| PubMedID- 21372353 | Profile of hepatic encephalopathy in children with cirrhosis and response to lactulose. |
| PubMedID- 26288637 | The most widely accepted definition is proposed by the american association for the study of liver diseases (aasld), which includes evidence of coagulopathy (international normalization ratio [inr] ≥ 1.5) and presence of encephalopathy in a patient without pre-existing cirrhosis and with an illness of less than 26 weeks duration (2). |
| PubMedID- 23006459 | Minimal hepatic encephalopathy in patients with cirrhosis by measuring liver stiffness and hepatic venous pressure gradient. |
| PubMedID- 22666568 | In cirrhosis the onset of hepatic encephalopathy is related to precipitating factors that expose the brain to toxins. |
| PubMedID- 20943084 | Results: serum cps-i and oct levels in cirrhosis patients with hepatic encephalopathy were (143.3+/-48.5) u/l, (297.0+/-102.6) is multiplied by 10 u/l, which were lower than that in cirrhosis patients without hepatic encephalopathy (180.3+/-51.5) u/l, (351.8+/-109.0) is multiplied by 10 u/l (t = 2.53, t = 2.78, p < 0.01). |
| PubMedID- 22195250 | Patients were considered to have acute liver failure (alf) according to the widely accepted definition of alf, which includes evidence of coagulation abnormality, usually an international normalized ratio (inr) ≥1.5, and any degree of mental alteration (encephalopathy) in a patient without pre-existing cirrhosis and with an illness of <26 weeks duration, with the exception of liver cirrhosis caused by vertically-acquired hbv if the disease has been recognized for <26 weeks.5 the definition for acute renal failure (arf) was an increase in serum creatinine concentration ≥0.5 mg/dl or by 50% compared with baseline value.6 gastrointestinal bleeding was defined as when patients presented with hematemesis, melena or hematochezia and had a drop in hemoglobin ≥1.5 g/dl. |
| PubMedID- 23166628 | Type 2 diabetes mellitus has also been found associated with hepatic encephalopathy in patients with hcv-related cirrhosis [8]. |
| PubMedID- 20602681 | Risk factors for hepatic encephalopathy in patients with cirrhosis and refractory ascites: relevance of serum sodium concentration. |
| PubMedID- 21234351 | Several controlled clinical studies reported no efficacy of bcaas on encephalopathy grade in patients with cirrhosis [95, 96]. |
| PubMedID- 21187868 | Ascites is the most common of the three major complications of cirrhosis together with hepatic encephalopathy and variceal hemorrhage. |
| PubMedID- 21922877 | The aim of this study was to asses the efficacy of probiotics in minimal hepatic encephalopathy in patients with cirrhosis of the liver. |
| PubMedID- 22870180 | Here we report on a patient suffered from liver cirrhosis with recurrent hepatic encephalopathy who developed mnz-induced neurotoxicity. |
| PubMedID- 24628464 | Background: safety of individual probiotic strains approved under investigational new drug (ind) policies in cirrhosis with minimal hepatic encephalopathy (mhe) is not clear. |
| PubMedID- 25420740 | However, it is often very difficult to differentiate between cryptococcal meningitis and hepatic encephalopathy in patients with liver cirrhosis, and there is delay in making the diagnosis. |
| PubMedID- 23225825 | Previously studies have investigated the effect of propofol on sub-clinical hepatic encephalopathy in patients with compensated liver cirrhosis.11,18 these studies found that propofol sedation during upper gastrointestinal endoscopy did not cause acute deterioration of sub-clinical hepatic encephalopathy.11,18 however, in patients with liver cirrhosis, hepatic function reserve is quite limited, and a cirrhotic liver is less tolerant to hemodynamic changes and surgical stress.1 therefore, anesthetic agents should be titrated with caution in cirrhotic patients to minimize the adverse effects of drugs and to stabilize hemodymanics. |
| PubMedID- 21306407 | Results: it was generally agreed that severity assessment of hepatic encephalopathy in patients with cirrhosis, whether made clinically or more objectively, should be continuous rather than categorical, and a system for assessing the sonic (spectrum of neuro-cognitive impairment in cirrhosis) was proposed. |
| PubMedID- 25528831 | The data on the positive experience with hepatic encephalopathy in patients with cirrhosis liver l-ornithine-l-aspartate (drug larnamyn), the effectiveness of which is provided by its components (amino acids, ornithine and aspartate) which improve metabolism, ammonia detoxification mechanism, production of energy in the krebs cycle, promote restoration of the cell membrane, and carried out anti-inflammatory and detoxicative effect. |
| PubMedID- 25674427 | Supplementation with bcaas normalizes amino acid profiles, ameliorates complications such as encephalopathy and hypoalbuminemia in patients with liver cirrhosis (kawaguchi et al. |
| PubMedID- 26417275 | In a prospective, randomized controlled trial conducted by lunia et al., probiotics were found to be effective in preventing hepatic encephalopathy in patients with cirrhosis (lunia et al., 2013[104]). |
| PubMedID- 23626595 | Even if a patient has liver cirrhosis with hepatic encephalopathy, liver cirrhosis should not be considered to be the only cause of hyperammonemia. |
| PubMedID- 23742732 | Prospective randomized clinical trials that compared the effects of zinc supplementation with those of no intervention, placebo, or standard therapy on hepatic encephalopathy in patients with liver cirrhosis were included. |
| PubMedID- 23731902 | Background: the aim of the present study was to examine the association of diabetes mellitus (dm) with the prevalence and severity of hepatic encephalopathy (he) in patients with decompensated cirrhosis (dc) and determine the impact of age and gender on this relationship. |
| PubMedID- 21406085 | The criteria for alf[17]: (aasld position paper: the management of acute liver failure, 2005) include evidence of coagulation abnormality, usually an inr ≥ 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of < 26 weeks duration. |
| PubMedID- 23986848 | A large spontaneous portal-systemic shunt is the most frequent cause of recurrent or persistent hepatic encephalopathy in patients with cirrhosis and no history of surgical or transhepatic portosystemic shunts; this was true in 71% of patients in a recent case-control study (13). |
| PubMedID- 25068951 | Among the 130 patients who survived ≥90 days after admission, 66 (51%) were complicated by liver cirrhosis, including 22 with encephalopathy, and 21 with ascites. |
| PubMedID- 25212730 | Embolization of spontaneous splenorenal shunt for after-tips hepatic encephalopathy in a patient with cirrhosis and variceal bleeding. |
| PubMedID- 23485720 | Lactulose is highly potential in prophylaxis of hepatic encephalopathy in patients with cirrhosis and upper gastrointestinal bleeding: results of a controlled randomized trial. |
| PubMedID- 23158131 | The aims of this study were to reveal the significance of cohb in patients with hepatitis b virus-related cirrhosis (hbc) complicated by hepatic encephalopathy (he), and to further investigate the influence of the ho/co pathway on the end-stage cirrhosis, hoping to find a reliable indicator to evaluate the course of hbc. |
| PubMedID- 24665321 | Blood ammonia levels are often measured in patients with cirrhosis suspected of having hepatic encephalopathy, but this is not a trustworthy indicator, because many conditions and even prolonged application of tourniquet during blooddrawing can elevate blood ammonia levels (table 4). |
| PubMedID- 23463488 | Satavaptan did not reduce the frequency of hepatic encephalopathy in patients with cirrhosis and ascites. |
| PubMedID- 26082668 | cirrhosis leading to hepatic encephalopathy is associated with abnormal protein and amino acid metabolism and a decreased fisher’s ratio (the molar ratio of branched-chain amino acids [bcaas] [leucine, valine, isoleucine] to aromatic amino acids [phenylalanine, tyrosine {tyr}]). |
| PubMedID- 20939401 | Hepatic encephalopathy in patients with cirrhosis may present under various clinical aspects, although minimal and episodic forms are the most frequent in clinical practice. |
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