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PedAM

Pediatric Disease Annotations & Medicines




Disease encephalopathy
Phenotype C0004153|atherosclerosis
Sentences 1
PubMedID- 23596414 Caa (except for familial caa cases) is usually not associated with thalamic or hippocampal infarcts, although capillary caa-associated vessel occlusion have been reported in the ca1-subiculum and thalamus (thal et al., 2008, 2009).watershed or borderzone (cortico-subcortical) infarcts in cerebral convexities or end-field territories between small deep and superficial vessels (hippocampal, thalamic infarcts) caused by diminished perfusion due to atherosclerosis, prolonged episodes of hypotension.subcortical arteriosclerotic (leuko) encephalopathy type binswanger (sae) associated with confluent wmls or “leukoaraoisis.” the pathology of wmls includes a triad of demyelination, axonal loss and lacunar infarcts in the periventricular/deep and subcortical white matter ranging from dilatation of the virchow–robin spaces to diffuse myelin pallor and microinfarcts, usually sparing the subcortical u-fibers related to the specific pattern of vascular supply.

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