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PedAM

Pediatric Disease Annotations & Medicines




Disease encephalitis
Phenotype C0039538|teratoma
Sentences 18
PubMedID- 25574194 Dalmau et al (22) first described a number of cases of encephalitis with ovarian teratoma that were associated with the nmdar antibodies, and subsequently analyzed the characteristics of 100 patients (35): 56% had ovarian teratoma, and the patients that received early tumor treatment and immunotherapy had an improved outcome.
PubMedID- 24965744 In young women affected with nmdr encephalitis associated with teratoma, surgical removal of the tumor in combination with plasma exchange, steroid and intravenous immunoglobulin may yield almost complete recovery (tanyi et al.
PubMedID- 25667873 Since its original description in 2007, anti-n-methyl-d-aspartate receptor (anti-nmdar) encephalitis associated with an ovarian teratoma is an increasingly recognized etiology of previously unexplained encephalopathy and encephalitis.
PubMedID- 22295267 A case of paraneoplastic limbic encephalitis associated with ovarian teratoma and n-methyl-d-aspartate receptor antibodies.
PubMedID- 25024565 Hence, screening for ovarian teratoma in females with nmad receptor encephalitis is important.
PubMedID- 21823510 [a case of anti-n-methyl-d-aspartate receptor encephalitis with ovarian teratoma showing excellent recovery with decreasing of anti-n-methyl-d-aspartate receptor antibody].
PubMedID- 21457154 Paraneoplastic limbic encephalitis associated with ovarian teratoma has recently been related to the development of antibodies to specific heteromers of the n-methyl-d-aspartate receptor and exhibits various manifestations including psychiatric symptoms, hypoventilation, seizures and derangement of autonomic nervous system function.
PubMedID- 20638543 Anti-n-methyl-d-aspartate receptor encephalitis associated with an ovarian teratoma in an adolescent female.
PubMedID- 26475263 The patients with anti-nmdar encephalitis complicated by ovarian teratoma require surgical treatment under general anesthesia.
PubMedID- 24211006 This type of encephalitis is often associated with ovarian teratoma in young women, but children are less likely to have tumors.
PubMedID- 23316239 Other authors stated that this encephalitis occurs in patients without teratoma and that men as well as children are affected [8].
PubMedID- 24959363 Among reports in the english language literature our case was the smallest ovarian teratoma associated with anti-nmdar encephalitis that was diagnosed before surgery or autopsy and subsequently completely removed by laparoscopic surgery.
PubMedID- 26136751 Associations of anti-nmda-receptor encephalitis with ovarian teratoma have been described (291).
PubMedID- 24741580 All these neurological immune-mediated syndromes share some clinical features such as a combination of generally hyperkinetic movement disorders with different degrees of complexity (from subtle chorea to typical upper limb stereotypies in paraneoplastic anti-nmdar encephalitis associated with ovarian teratoma) and neuropsychiatric symptoms, subacute onset, progressing within days or weeks, and response to steroids, intravenous immunoglobulins, immunosuppressive agents, plasmapheresis, and monoclonal antibodies such as rituximab.
PubMedID- 20434635 It has been shown that patients suffering from paraneoplastic encephalitis associated with ovarian teratoma display antibodies for anti-n-methyl-d-aspartate (nmda) receptors in csf or plasma (more specifically for the nr1 subunit of the nrl/nr2 heteromers required to form a functional nmda receptor).
PubMedID- 24097319 On the basis of these data, anti-n-methyl-d-aspartate receptor (nmdar) encephalitis associated with ovarian teratoma was suspected, and the right ovariectomy was performed.
PubMedID- 24969336 Conclusions: ovarian teratoma with anti-nmdar encephalitis always presents with psychiatric symptoms which could be misdiagnosed as psychiatric diseases.
PubMedID- 25672700 To clarify the pathogenesis of anti-n-methyl-d-aspartate receptor (nmdar) encephalitis in patients without ovarian teratoma, we investigate normal human ovary, normal bovine ovary and bovine ova.

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