PedAM
Pediatric Disease Annotations & Medicines
| Disease | encephalitis |
| Phenotype | C0013384|dyskinesias |
| Sentences | 2 |
| PubMedID- 24465246 | It has now been suggested that the nmdar antibody interferes with glutamatergic signalling by selectively decreasing the number of nmdar clusters in the postsynaptic density.161) in fact, prominent psychiatric symptoms such as psychosis, catatonia-like symptoms and dyskinesias in patients with encephalitis162,163) can be triggered by igg serum and csf antibodies that are directed against extracellular epitopes of the nr1a subunit of nmdars.164) recent studies found that approximately 5-10% of scz cases were associated with serum and csf autoantibodies to the nmdar.165-167) importantly, the repertoire of antibody subtypes in scz has now been shown to differ from nmdar encephalitis,167) potentially revealing a novel method to reaffirm the diagnosis of scz and provide more effective immunomodulatory treatment strategies. |
| PubMedID- 23465509 | Caspr2 antibodies in limbic encephalitis with cerebellar ataxia, dyskinesias and myoclonus. |
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