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PedAM

Pediatric Disease Annotations & Medicines




Disease dysentery
Phenotype C0013371|shigella
Sentences 13
PubMedID- 24086068 As opposed to other invasive pathogens that reside into host cells in a parasitic mode, shigella, the causative agent of bacillary dysentery, invades the colonic mucosa but does not penetrate further to survive into deeper tissues.
PubMedID- 26313003 shigella, the etiological agent of bacillary dysentery in humans [7], is an interesting example since during the evolutionary transition from its innocuous ancestor, e. coli, its polyamine profile has undergone drastic changes.
PubMedID- 23818998 The minute inoculum (ten shigella organisms) capable of causing full blown dysentery enables direct person-to-person transmission [1], [2], even where environmental sanitation is otherwise adequate and safe water is available [3], [4].
PubMedID- 25192335 Coli ancestor, shigella, the aetiological agent of bacillary dysentery, has undergone drastic genomic rearrangements affecting the polyamine profile.
PubMedID- 25353930 Our model system, shigella flexneri, the agent of human bacillary dysentery, uses its t3ss to invade gut epithelial cells.
PubMedID- 23318141 shigella, the causative agent of bacillary dysentery, invades the colonic epithelium where it elicits an intense inflammation leading to tissular destruction.
PubMedID- 23819110 For example, davison43 isolated flexner's bacillus (shigella flexneri) from 10 of 12 cases of dysentery in children.
PubMedID- 22347577 Background and objectives: shigella, causative of bacillary dysentery, has two colony forms.
PubMedID- 24863068 Antibody-mediated immunity to shigella, the causative agent of bacillary dysentery, requires several episodes of infection to get primed and is short-lasting, suggesting that the b cell response is functionally impaired.
PubMedID- 21669399 shigella, the causative agent of bacillary dysentery in humans, invades epithelial cells, using a type iii secretory system (t3ss) to inject bacterial effectors into host cells and remodel the actin cytoskeleton.
PubMedID- 23898465 In models of gut infection, rabbits treated with a neutralizing anti-cd14 antibody exhibited a remarkably higher susceptibility to infections with shigella, the cause of bacillary dysentery (wenneras et al., 2001).
PubMedID- 20089698 The t cell response to shigella, the causative agent of bacillary dysentery, remains poorly understood.
PubMedID- 23463010 shigella, the agent of bacillary dysentery, invades epithelial cells by locally inducing actin reorganization.

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