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PedAM

Pediatric Disease Annotations & Medicines




Disease dwarfism
Phenotype C0028326|noonan syndrome
Sentences 2
PubMedID- 20981140 The pediatric indications for recombinant human gh approved by the united states food and drug administration (fda) include treatment of children with growth failure due to gh deficiency; children with short stature associated with noonan syndrome (ns), turner syndrome (ts), and prader-willi syndrome (pws); children with short stature born small for gestational age (sga) who have not reached normal growth range by age 2–4 years; short stature with homeobox-containing gene deficiency; children with chronic renal insufficiency; children with idiopathic short stature (iss) who are >2.25 standard deviations (sd) below the mean in height and who are unlikely to catch up in height [1–4].
PubMedID- 22157403 Purpose of review: we review recent developments in the approach to the treatment of short stature in patients with turner and noonan syndromes.

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