PedAM
Pediatric Disease Annotations & Medicines
| Disease | down syndrome |
| Phenotype | C0679466|cognitive deficits |
| Sentences | 6 |
| PubMedID- 21816951 | The use of mouse models to understand and improve cognitive deficits in down syndrome. |
| PubMedID- 22541289 | Pathways to cognitive deficits in down syndrome. |
| PubMedID- 21029075 | cognitive deficits in down syndrome: narrowing 'down' to olig1 and olig2. |
| PubMedID- 21447382 | These results imply that alpha-tocopherol supplementation from an early stage may be an effective treatment for the cognitive deficits associated with down syndrome. |
| PubMedID- 24801365 | cognitive deficits in down syndrome (ds) have been linked to increased synaptic inhibition, leading to an imbalance of excitation/inhibition (e/i). |
| PubMedID- 22898099 | The cognitive deficits in down syndrome (ds) are attributed to an excessive hippocampal inhibition, which obstructs neuronal plasticity and normal learning and memory, a view which is largely based on studies of ts65dn mice, the best characterized mouse model of ds. |
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