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PedAM

Pediatric Disease Annotations & Medicines




Disease down syndrome
Phenotype C0026654|moyamoya
Sentences 4
PubMedID- 23149966 The 26-fold-greater prevalence of down syndrome in patients with coexisting moyamoya disease compared with the prevalence of down syndrome among live births (145 per 100,000) highlights the need for a better understanding of the common pathophysiology of the 2 conditions.
PubMedID- 26180607 Although this study contained only surgically treated patients, moyamoya syndrome associated with down syndrome appears to be a clinically aggressive disorder.
PubMedID- 20543230 The authors report a 32-year-old male who presented transient stenosis of the bilateral posterior cerebral artery (pca) one week after right sta-mca anastomosis and indirect bypass for quasi-moyamoya disease associated with down syndrome.
PubMedID- 24416050 The exact mechanism of vascular occlusion in down syndrome with moyamoya syndrome is unknown, although several hypotheses have been proposed6-11).

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