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PedAM

Pediatric Disease Annotations & Medicines




Disease down syndrome
Phenotype C0025362|mental retardation
Sentences 4
PubMedID- 21909210 He also suffered mental retardation due to down syndrome since birth.
PubMedID- 20528079 In addition to mental retardation, individuals with down syndrome (ds) also develop the neuropathological changes typical of alzheimer's disease (ad) and the majority of these individuals exhibit dementia.
PubMedID- 21266456 mental retardation in down syndrome (ds) appears to be related to severe neurogenesis impairment during critical phases of brain development.
PubMedID- 22115353 However, excessive production of hydrogen sulfide, by using inorganic hydrogen sulfide donors such as nahs, may contribute to the pathogenesis of inflammatory diseases, septic shock, cerebral stroke and mental retardation in patients with down syndrome.

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