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PedAM

Pediatric Disease Annotations & Medicines




Disease diarrhea
Phenotype C0027947|neutropenia
Sentences 8
PubMedID- 22870042 Among toxicities, the differences in the risks of neutropenia with hospitalization, diarrhea, nausea, and fatigue had the most impact on preferences; the risk differences of myalgia, stomatitis, and hand-foot syndrome had the least.
PubMedID- 23429739 Severe neutropenia occurred in 47% of patients, and severe diarrhea occurred in 47% of patients.
PubMedID- 22382883 The maximal tolerated dose (mtd) was reached at 300 mg/day where 2 patients out of 6 experienced a dose limiting toxicity (febrile neutropenia with diarrhea).
PubMedID- 26266093 Nine days after chemotherapy, the patient presented a febrile neutropenia with worsening diarrhea, intermittent nausea, vomiting, and acute abdominal pain.
PubMedID- 23055694 Important side effects include neutropenia, elevation of liver enzymes, diarrhea, infections, and elevation of blood pressure.
PubMedID- 20308874 Grades 3 and 4 hematological toxicities were neutropenia in 44% of patients, grade 2-3 diarrhea in 14% of patients, and grade 2 neuropathy in 12 patients.
PubMedID- 22253528 Grade 3/4 toxicities included neutropenia in 6–46% of patients, diarrhea in 4–33% of patients, skin toxicity in 6–24% of patients, and anaphylaxis to cetuximab in <5% of patients.
PubMedID- 23476759 A total of 412 citations were identified for two cancer-treatment-related symptoms of diarrhea and fever with neutropenia (see figure 1).

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