PedAM
Pediatric Disease Annotations & Medicines
| Disease | diarrhea |
| Phenotype | C0020538|hypertension |
| Sentences | 5 |
| PubMedID- 26075440 | These were hypertension (in 67.8% of the patients), diarrhea (in 59.4%), fatigue or asthenia (in 59.0%), decreased appetite (in 50.2%), decreased weight (in 46.4%) and nausea (in 41.0%). |
| PubMedID- 24748771 | The dose-limiting toxicity was grade 3 proteinuria, observed in two patients at 32 mg, and the maximum tolerated dose was defined as 25 mg. the most frequent drug-related toxicities were hypertension (40% of patients), diarrhea (45%), nausea (37%), stomatitis (32%), proteinuria (26%) and vomiting (23%). |
| PubMedID- 25874010 | Univariate analysis revealed that s-1 discontinuation was not significantly associated with age, s-1 modification/dose reduction during treatment, surgical procedure, complications including diabetes mellitus or hypertension, prescription of prophylactic antidiarrheal, laxative, probiotic, and antiemetic agents, prescription of therapeutic antidiarrheal, probiotic, and antiemetic agents, side effects including vomiting, diarrhea, stomatitis, anorexia, dysgeusia, pigmentation, skin rash, lacrimation, anemia, thrombocytopenia, and others. |
| PubMedID- 19690858 | The most frequent nonhematologic traes included hypertension (63% of patients), diarrhea (51%), and fatigue (43%). |
| PubMedID- 20458050 | Grade 3/4 toxicities included hypertension (four of 31; 12.9%); diarrhea (two of 31; 6.4%); and fatigue (six of 31; 19.4%). |
Page: 1