PedAM
Pediatric Disease Annotations & Medicines
| Disease | diabetes mellitus, insulin-dependent |
| Phenotype | C0020598|hypoglycaemia |
| Sentences | 49 |
| PubMedID- 21737469 | We selected for inclusion only studies that were randomised controlled trials and that compared glycaemic control and hypoglycaemia in participants with type 1 diabetes treated by intensive insulin therapy (multiple daily insulin injections or continuous subcutaneous insulin infusion) where either real time continuous glucose monitoring or self monitoring of blood glucose was used throughout the study for at least two months. |
| PubMedID- 26044206 | The current result might be related to a lower frequency of nocturnal hypoglycaemia in individuals with type 1 diabetes who use ideg as basal insulin [12–14]. |
| PubMedID- 25985748 | We studied whether infrared thermography can detect ts changes during hypoglycaemia in patients with type 1 diabetes and how the ts response differs between patients with normal hypoglycaemia awareness and hypoglycaemia unawareness. |
| PubMedID- 24057153 | This is the first study to examine how the ultra-long-acting basal insulin ideg (estimated duration of action >42 h) affects the hypoglycaemic response during development of, and recovery from, hypoglycaemia in patients with type 1 diabetes. |
| PubMedID- 23121373 | Disrupted performance in simulated driving has been demonstrated during hypoglycaemia in people with type 1 diabetes [12,13]. |
| PubMedID- 25810037 | Islet transplantation is of proven efficacy in type 1 diabetes complicated by hypoglycaemia, but it is not known if nationally funded programmes reach the socioeconomically deprived. |
| PubMedID- 24023652 | The aim of this study was to investigate whether copeptin increases upon hypoglycaemia in patients with type 1 diabetes mellitus and is associated with the degree of hypoglycaemia awareness. |
| PubMedID- 22371161 | Continuous subcutaneous insulin infusion (csii, or insulin pump therapy) reduces hba1c levels and hypoglycaemia in patients with type 1 diabetes mellitus (t1dm) compared with multiple daily insulin injections (mdi). |
| PubMedID- 23821450 | [rare cause of recurrent hypoglycaemia in type 1 diabetes mellitus--case 6/2013]. |
| PubMedID- 25070348 | Effects of angiotensin ii receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes. |
| PubMedID- 24123789 | The beta-cell replacement by islet transplantation is an attractive approach for normalizing blood glucose without hypoglycaemia in patient with type 1 diabetes mellitus (t1d). |
| PubMedID- 22727048 | The study is a danish two-year investigator-initiated, prospective, randomised, open, blinded endpoint (probe), multicentre, cross-over trial investigating the effect of insulin analogues versus human insulin on the frequency of severe hypoglycaemia in subjects with type 1 diabetes. |
| PubMedID- 21951030 | Evaluating the cost-effectiveness of reduced mild hypoglycaemia in subjects with type 1 diabetes treated with insulin detemir or nph insulin in denmark, sweden, finland and the netherlands. |
| PubMedID- 24185859 | Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention. |
| PubMedID- 20873363 | Conclusions: insulin pump therapy has additional qualitative benefits beyond improvements in glycaemic control and reducing the risk of hypoglycaemia for people with type 1 diabetes. |
| PubMedID- 20215476 | Introduction: high renin-angiotensin system (ras) activity has been associated with a high risk of severe hypoglycaemia in patients with type 1 diabetes and with cognitive deterioration during experimental hypoglycaemia in healthy subjects. |
| PubMedID- 22417321 | Conclusions: rates of severe hypoglycaemia in youth with type 1 diabetes remain high. |
| PubMedID- 20132542 | We have no clear explanation why our results indicate a lower impact on hrqol of fear of hypoglycaemia in individuals with type 1 diabetes than those with type 2 diabetes. |
| PubMedID- 24965522 | Aim: to describe mood and psychosensorial symptoms of hypoglycaemia in adolescents with type 1 diabetes mellitus in two countries with different cultures, turkey and the usa. |
| PubMedID- 24320159 | Are bedtime nutritional strategies effective in preventing nocturnal hypoglycaemia in patients with type 1 diabetes. |
| PubMedID- 20546285 | Frequency of biochemical hypoglycaemia in adults with type 1 diabetes with and without impaired awareness of hypoglycaemia: no identifiable differences using continuous glucose monitoring. |
| PubMedID- 24805141 | Coeliac disease presenting as severe hypoglycaemia in youth with type 1 diabetes. |
| PubMedID- 25855340 | Counter-regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo-controlled, double-blind, crossover trial. |
| PubMedID- 20854383 | Fear of hypoglycaemia in adults with type 1 diabetes. |
| PubMedID- 26213236 | Sustained benefit of continuous subcutaneous insulin infusion on glycaemic control and hypoglycaemia in adults with type 1 diabetes. |
| PubMedID- 21493665 | Conclusion: these two small crossover trials suggest that closed loop delivery of insulin may improve overnight control of glucose levels and reduce the risk of nocturnal hypoglycaemia in adults with type 1 diabetes. |
| PubMedID- 23266467 | Fear of hypoglycaemia in patients with type 1 diabetes: do patients and diabetologists feel the same way. |
| PubMedID- 24687395 | Secondary diabetic ketoacidosis and severe hypoglycaemia in patients with established type 1 diabetes mellitus in china: a multicentre registration study. |
| PubMedID- 24654672 | It has been estimated that the incidence rate for emergency treatment of severe hypoglycaemia in people with type 1 diabetes is ˜11.5 per 100 patients-years 11. in that study, the associated cost was estimated to be ˜£6.5 m across the uk. |
| PubMedID- 20121892 | The results suggest that future interventions should target both the parents' fear and appropriate ways to prevent hypoglycaemia in children with type 1 diabetes. |
| PubMedID- 21188352 | Melatonin decreases insulin sensitivity, can decrease insulin secretion and can increase blood glucose levels, while phototherapy sessions (which potentially decrease melatonin levels) have been shown to induce recurrent hypoglycaemia in a patient with type 1 diabetes [24–26]. |
| PubMedID- 24794703 | Effect of insulin analogues on risk of severe hypoglycaemia in patients with type 1 diabetes prone to recurrent severe hypoglycaemia (hypoana trial): a prospective, randomised, open-label, blinded-endpoint crossover trial. |
| PubMedID- 22047939 | The effect of short-term use of the guardian rt continuous glucose monitoring system on fear of hypoglycaemia in patients with type 1 diabetes mellitus. |
| PubMedID- 23413806 | The preservation of insulin secretion often seen for an initial period after diagnosis of type 1 diabetes is associated with reduced hypoglycaemia and glycaemic variability, improved hba1c and lower insulin requirements [92,123]. |
| PubMedID- 26173655 | Conclusions: caffeine intake should be considered as another strategy that may modestly attenuate hypoglycaemia in individuals with type 1 diabetes during exercise, but should be taken with precautionary measures as it may increase the risk of late-onset hypoglycaemia. |
| PubMedID- 22175008 | This pilot data suggests that gln supplementation increases the likelihood of postexercise overnight hypoglycaemia in adolescents with type 1 diabetes. |
| PubMedID- 25763988 | Behavioural interventions targeting problem-solving skills could be considered as practical, non-pharmacological strategies to reduce hypoglycaemia in adolescents with type 1 diabetes. |
| PubMedID- 25694217 | Effects of sitagliptin on counter-regulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double-blind placebo-controlled crossover study. |
| PubMedID- 25683747 | Conclusions: a weight-based protocol of 0.3 g/kg glucose appears more effective for treating symptomatic hypoglycaemia in adults with type 1 diabetes than either the most common current recommendation of 15 g glucose or a 0.2 g/kg glucose dose. |
| PubMedID- 25053672 | Recurrent hypoglycaemia in a patient with type 1 diabetes. |
| PubMedID- 20633252 | The authors conclude that future interventions should target both parental fear and appropriate ways to prevent hypoglycaemia in children with type 1 diabetes [28]. |
| PubMedID- 24088368 | The rate of severe and moderate hypoglycaemia in patients with iddm was more than two-fold that in other patient subgroups (table 3). |
| PubMedID- 21323815 | Improvements in real-time continuous glucose monitoring and optimisation of basal insulin dosing may offer significant benefit to preventing hypoglycaemia in patients with type 1 diabetes who regularly exercise. |
| PubMedID- 20377657 | In fact, there is nearly a threefold increase in hypoglycaemia with intensification of treatment in type 1 diabetes (1). |
| PubMedID- 22258980 | Diabetes complications, death and costs were not measured.there were no studies in pregnant women with diabetes type 1 and in patients with hypoglycaemia unawareness. |
| PubMedID- 21309845 | Frequency of symptomatic and asymptomatic hypoglycaemia in type 1 diabetes: effect of impaired awareness of hypoglycaemia. |
| PubMedID- 21812638 | High serum ace activity predicts severe hypoglycaemia over time in patients with type 1 diabetes. |
| PubMedID- 26312919 | Results from hospital-based studies have shown improved overnight glucose control and reduced risk of hypoglycaemia in type 1 diabetes. |
| PubMedID- 25764474 | Fear of hypoglycaemia in adults with type 1 diabetes: results from diabetes miles - the netherlands. |
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