PedAM
Pediatric Disease Annotations & Medicines
| Disease | diabetes mellitus, insulin-dependent |
| Phenotype | C0011881|diabetic nephropathy |
| Sentences | 57 |
| PubMedID- 26167956 | Genome-wide pathway analysis for diabetic nephropathy in type 1 diabetes. |
| PubMedID- 25634228 | Aims/hypothesis: the aim of this study was to assess how physical activity predicts the development and progression of diabetic nephropathy in patients with type 1 diabetes. |
| PubMedID- 25871838 | Differential gene expression in diabetic nephropathy in individuals with type 1 diabetes. |
| PubMedID- 24029427 | Sex and genetic variation influence the risk of developing diabetic nephropathy and esrd in patients with type 1 diabetes. |
| PubMedID- 25686570 | Prevention: intensive exercise associated with reduced risk of diabetic nephropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 26212019 | Objective: the aim of this study was to investigate serum levels of mannose-binding lectin (mbl) in type 1 diabetes with diabetic nephropathy (dn) and persistent normoalbuminuria (pn). |
| PubMedID- 26339138 | A very recent publication reports a close association between ficolin and diabetic nephropathy in patients with type 1 diabetes [19]. |
| PubMedID- 19563389 | Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes. |
| PubMedID- 22608880 | Associations of sod1 gene variants with diabetic nephropathy were reported in patients with type 1 diabetes. |
| PubMedID- 22643932 | It is, however, not known whether such snps also confer susceptibility to diabetic nephropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 21192815 | To date, it has been shown to be reproducible in healthy volunteers[23,24] and to detect increased wall thickness in selected patients with known coronary artery disease, type 1 diabetes complicated by diabetic nephropathy, and asymptomatic individuals from the mesa study[10,12-14,25]. |
| PubMedID- 25622104 | The possible benefit of lasp1 as a biomarker is not restricted to cancer, as lasp1 is one out of 12 differentially expressed proteins that show decreased expression in cultured skin fibroblasts of insulin-dependent type 1 diabetes mellitus patients with diabetic nephropathy versus diabetics without nephropathy or healthy subjects. |
| PubMedID- 22819809 | Introduction: persistent microalbuminuria is the accepted marker for early detection of a high risk of developing diabetic nephropathy in patients diagnosed with type i diabetes mellitus. |
| PubMedID- 20460425 | To determine whether the genetic variations identified through the gwass on european americans with type 1 diabetes are associated with susceptibility to diabetic nephropathy in japanese individuals with type 2 diabetes, we studied the association between the snps in the above four loci and diabetic nephropathy in japanese subjects with type 2 diabetes. |
| PubMedID- 19395281 | Endoglin expression levels and diabetic nephropathy risk in patients with type 1 diabetes. |
| PubMedID- 25109108 | Association of renin-angiotensin system genes polymorphism with progression of diabetic nephropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 20191117 | The purpose of this study is to assess the possible association of +35a/c (rs2234694) polymorphism in sod1-gene with advanced stages of diabetic nephropathy in patients with type 1 diabetes in romania. |
| PubMedID- 25713706 | [25] also assessed mirna expression in the uevs from diabetes mellitus type 1 with or without diabetic nephropathy and reported that uevs derived from microalbuminuric patients were enriched in mir-130a and mir-145. |
| PubMedID- 25032099 | Although diabetic nephropathy due to type 1 diabetes mellitus (t1dm) has been studied more extensively, the vast majority of the diabetic ckd patients suffer from type 2 diabetes mellitus (t2dm). |
| PubMedID- 24172700 | Severe diabetic nephropathy in type 1 diabetes and pregnancy--a case series. |
| PubMedID- 20667095 | Variation of creatinine and cystatin levels among female and male type 1 diabetes patients with diabetic nephropathy according to the genotypes of leu359ile variant in the mcf2l2 gene. |
| PubMedID- 21747824 | Abnormal excretion of protein is a clinically relevant indicator of impending diabetes-related renal damage; however, mechanisms underlying proteinuria in diabetic nephropathy associated with type 1 diabetes mellitus (t1d) are not completely understood. |
| PubMedID- 22696035 | diabetic nephropathy in type 1 diabetes: has the outlook improved since the 1980s. |
| PubMedID- 23543049 | Conclusion: the association of snp loci derived from gwas in european type 1 diabetes with diabetic nephropathy was not replicated in the japanese patients with type 2 diabetes, although the erbb4 locus may have some effect also in japanese type 2 diabetes. |
| PubMedID- 25575985 | Methods: the most recent childbirth of 108 consecutive type 1 diabetes patients with diabetic nephropathy and a singleton pregnancy were studied. |
| PubMedID- 24688725 | To this end the summit consortium has assembled and phenotyped the largest genome-wide association study (gwas) database for type 1 diabetes patients with diabetic nephropathy (dn). |
| PubMedID- 23346076 | Obviously, the heterozygous index is high compared to the percentage of homozygous and increased from the group of non-diabetic control subjects, to type 1 diabetes (t1d) patients without diabetic nephropathy and the patients with diabetic nephropathy. |
| PubMedID- 24667182 | Therefore, pemt inhibitors may be useful in the treatment of diabetic nephropathy in patients with type 1 diabetes, as well as for other er stress- and oxidative stress-related diseases. |
| PubMedID- 24781861 | Objective: estimation of glomerular filtration rate (egfr) is one of the current clinical methods for identifying risk for diabetic nephropathy in subjects with type 1 diabetes (t1d). |
| PubMedID- 21321840 | This prospective study indicates that change in amount body fat and levels of inflammatory cytokines, such as il-6, contribute to change in insulin resistance over time in type 1 diabetes patients with and without diabetic nephropathy. |
| PubMedID- 20437026 | The relationship of retinal vessel diameter to changes in diabetic nephropathy structural variables in patients with type 1 diabetes. |
| PubMedID- 24658196 | Haptoglobin genotype and risk of diabetic nephropathy in patients with type 1 diabetes mellitus: a study on a spanish population. |
| PubMedID- 23317710 | The patient had a 16-year history of poorly controlled type 1 diabetes mellitus with end stage diabetic nephropathy requiring regular haemodialysis. |
| PubMedID- 23340892 | A recent study suggested that visit-to-visit variability in blood pressure was associated with the development of diabetic nephropathy in patients with type 1 diabetes (9). |
| PubMedID- 23877984 | Research design and methods: using the nationwide finnish diabetic nephropathy (finndiane) study cohort of 4,083 patients with type 1 diabetes (mean age of 37.4 +/- 11.8 years at enrollment), we analyzed the incidence of first-ever sah events. |
| PubMedID- 26239688 | Microalbuminuria provides the earliest clinical marker of diabetic nephropathy among patients with type 1 diabetes, yet it lacks sensitivity and specificity for early histological manifestations of disease. |
| PubMedID- 24587794 | In summary, our results show that the ppar gamma 2 polymorphism is unlikely to be associated with the development and progression of the diabetic nephropathy in patients with type 1 diabetes. |
| PubMedID- 21180245 | Further studies are necessary in order to demonstrate or exclude the role of cat gene in diabetic nephropathy in patients with type 1 diabetes. |
| PubMedID- 20687937 | Genome-wide dna methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. |
| PubMedID- 24918158 | Improved prognosis of diabetic nephropathy in type 1 diabetes. |
| PubMedID- 20490454 | Ddost, prkcsh and lgals3, which encode age-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes. |
| PubMedID- 20467478 | The frequency of minor allele (maf) a was 0.414 in the studied population, and no significant difference of the mafs between type 1 diabetes patients with and without diabetic nephropathy was found (0.411 vs. 0.416, p-values were 0.796, test with additive model, and 0.415, test for allele positivity, respectively). |
| PubMedID- 21330642 | Pulse pressure predicts incident cardiovascular disease but not diabetic nephropathy in patients with type 1 diabetes (the finndiane study). |
| PubMedID- 20332124 | Conclusions: these findings suggest a role of inflammation and endothelial dysfunction as markers and contributors of the development of diabetic nephropathy in persons with type 1 diabetes mellitus. |
| PubMedID- 22486725 | Aims: the metabolic syndrome is a frequent phenomenon in people with type 1 diabetes and is associated with diabetic nephropathy. |
| PubMedID- 22811694 | Specifically, in patients with diabetic nephropathy associated with type 1 diabetes, nisoldipine (long-acting dihydropyridine ccb) attenuates the rate of decline in glomerular filtration [16]. |
| PubMedID- 21909410 | Novel susceptibility locus at 22q11 for diabetic nephropathy in type 1 diabetes. |
| PubMedID- 21307382 | This study is part of the ongoing finndiane study, with the aim to identify genetic, clinical, and environmental risk factors for diabetic nephropathy in patients with type 1 diabetes (7,9). |
| PubMedID- 20188385 | Conversely, levels are elevated in type 1 diabetes mellitus (t1dm) and associated with microalbuminuria and diabetic nephropathy. |
| PubMedID- 24527422 | Continuous microalbuminuria (30-299 mg/day) appears in the early stages of diabetic nephropathy with type 1 diabetes, and it is an indicator of nephropathy onset and the development of cardiovascular disease [5]. |
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