PedAM

Pediatric Disease Annotations & Medicines

Disease	dementia
Phenotype	C0524851\|neurodegenerative diseases
Sentences	16
PubMedID- 24086754	Tauopathies, a heterogenous group of neurodegenerative diseases accompanied with dementia, are characterized by inclusions of the microtubule-binding protein tau.
PubMedID- 24324497	Whereas prion diseases are a rare form of neurodegenerative diseases leading to dementia, alzheimer's disease (ad) is the most common one.
PubMedID- 23585716	Ladostigil and m30 are multi target, so called, "dirty" drugs that were designed to answer the therapeutic requirements of progressive neurodegenerative diseases with features of dementia, behavioural abnormalities, depression and extrapyramidal symptoms in pd and ad.
PubMedID- 21559182	In sum, neurodegenerative diseases, with or without dementia, encompass a large spectrum of disorders.
PubMedID- 23214132	Because the average life span has lenghtened we hear more and more often about neurodegenerative diseases that lead to dementia or paralysis.
PubMedID- 20831835	This, in the light of the fact that amyloid-β peptide or thapsigargin causes er stress-induced apoptosis [42,43], raises the possibility that dlphtetn could also exert its beneficial action against dementia associated with neurodegenerative diseases.
PubMedID- 23771421	And mutations in dnmt1 can induce one form of neurodegenerative diseases with dementia and sensorineural hearing loss.
PubMedID- 25726296	Changes in hearing function are generally not a major focus of concern for persons with a majority of neurodegenerative diseases associated with dementia, such as alzheimer disease (ad).
PubMedID- 26052284	Such multi-factorial causes during the neuropathologic progression are common for the most prevalent neurodegenerative diseases of ad, als, frontotemporal dementia (ftd), parkinson’s disease (pd) and huntington’s disease (hd).
PubMedID- 23001356	Second, approximately 20% of mci patients, who progress to dementia, are diagnosed with neurodegenerative diseases other than ad, such as vascular, lewy body, huntington, parkinson, and other dementias [9,11].
PubMedID- 21735736	We considered the psychiatric symptoms and head ct findings of the present patient to be important observations for helping to discriminate between alzheimer disease or other neurodegenerative diseases with dementia, and ftld-tdp.
PubMedID- 25844871	Alpha-synuclein is one of two other amyloidogenic key proteins, specifically, amyloid beta (abeta) and tau, which play a major pathophysiological role in the three most common neurodegenerative diseases leading to dementia, namely alzheimer’s disease (ad), dlb and parkinson’s disease dementia (pdd).
PubMedID- 23049978	Cerebral aging is associated with the occurrence of neurodegenerative diseases leading to dementia such as alzheimer's disease (ad).
PubMedID- 24073234	Alzheimer’s and parkinson’s disease [pd] are the two most common neurodegenerative diseases of the elderly, while dementia with lewy bodies [dlb] is the second-most common form of dementia after alzheimer’s disease [ad].
PubMedID- 23383391	The recent discovery that mutations in the gene encoding for progranulin (grn) cause frontotemporal lobar degeneration (ftld), and other neurodegenerative diseases leading to dementia, has brought renewed interest in progranulin and its functions in the central nervous system.
PubMedID- 24018267	The discovery that mutations in the gene encoding for progranulin (grn) cause frontotemporal lobar degeneration (ftld) and other neurodegenerative diseases leading to dementia has brought renewed interest in progranulin and its functions in the central nervous system.

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