PedAM

Pediatric Disease Annotations & Medicines

Disease	dementia
Phenotype	C0524851\|neurodegenerative disease
Sentences	29
PubMedID- 25726296	Changes in hearing function are generally not a major focus of concern for persons with a majority of neurodegenerative diseases associated with dementia, such as alzheimer disease (ad).
PubMedID- 22242180	Alzheimer's disease (ad) is the most frequent form of neurodegenerative disease associated with dementia in the elderly.
PubMedID- 21645364	Loss of function mutations of the pgrn gene have been also reported to cause frontotemporal lobar degeneration (ftld), a neurodegenerative disease leading to dementia generally in the presenium.
PubMedID- 23986673	Ftld is the second most frequent neurodegenerative disease leading to early onset dementia after alzheimer's disease (ad).
PubMedID- 26052284	Such multi-factorial causes during the neuropathologic progression are common for the most prevalent neurodegenerative diseases of ad, als, frontotemporal dementia (ftd), parkinson’s disease (pd) and huntington’s disease (hd).
PubMedID- 24086754	Ad is characterized by intracellular inclusions of the microtubule binding protein tau which are also present in various other neurodegenerative diseases associated with dementia, referred to as tauopathies.
PubMedID- 25844871	Alpha-synuclein is one of two other amyloidogenic key proteins, specifically, amyloid beta (abeta) and tau, which play a major pathophysiological role in the three most common neurodegenerative diseases leading to dementia, namely alzheimer’s disease (ad), dlb and parkinson’s disease dementia (pdd).
PubMedID- 23214132	Because the average life span has lenghtened we hear more and more often about neurodegenerative diseases that lead to dementia or paralysis.
PubMedID- 25961991	Five (single amino acid) ns mutations are associated with severe neurodegenerative disease in man, leading to early onset dementia, epilepsy and neuronal death.
PubMedID- 24565007	Alzheimer's disease (ad) is a chronic neurodegenerative disease leading to cognitive decline, dementia, and ultimately death.
PubMedID- 21559182	In sum, neurodegenerative diseases, with or without dementia, encompass a large spectrum of disorders.
PubMedID- 20831835	This, in the light of the fact that amyloid-β peptide or thapsigargin causes er stress-induced apoptosis [42,43], raises the possibility that dlphtetn could also exert its beneficial action against dementia associated with neurodegenerative diseases.
PubMedID- 23771421	And mutations in dnmt1 can induce one form of neurodegenerative diseases with dementia and sensorineural hearing loss.
PubMedID- 25959573	Alzheimer’s disease (ad) is the most prevalent neurodegenerative disease associated with dementia, with more than 26 million cases worldwide in 2006 and an expected 106 million cases by 20501. little is known about the etiology of ad and the identification of a cure has remained elusive.
PubMedID- 24018267	The discovery that mutations in the gene encoding for progranulin (grn) cause frontotemporal lobar degeneration (ftld) and other neurodegenerative diseases leading to dementia has brought renewed interest in progranulin and its functions in the central nervous system.
PubMedID- 24324497	Whereas prion diseases are a rare form of neurodegenerative diseases leading to dementia, alzheimer's disease (ad) is the most common one.
PubMedID- 21735736	We considered the psychiatric symptoms and head ct findings of the present patient to be important observations for helping to discriminate between alzheimer disease or other neurodegenerative diseases with dementia, and ftld-tdp.
PubMedID- 22498202	Alzheimer's disease (ad) is a clinico-pathological diagnosis in which progressive neurodegenerative disease is associated with the dementia syndrome.
PubMedID- 20352044	Background: amyotrophic lateral sclerosis (als), a common late-onset neurodegenerative disease, is associated with fronto-temporal dementia (ftd) in 3-10% of patients.
PubMedID- 23585716	Ladostigil and m30 are multi target, so called, "dirty" drugs that were designed to answer the therapeutic requirements of progressive neurodegenerative diseases with features of dementia, behavioural abnormalities, depression and extrapyramidal symptoms in pd and ad.
PubMedID- 21087763	Loss-of-function mutations in the progranulin gene (grn) cause frontotemporal lobar degeneration (ftld), a progressive neurodegenerative disease affecting approximately 10% of early-onset dementia patients.
PubMedID- 24561250	Alzheimer's disease (ad) is a chronic, progressive and irreversible neurodegenerative disease with clinical characteristics of memory loss, dementia and cognitive impairment.
PubMedID- 23049978	Cerebral aging is associated with the occurrence of neurodegenerative diseases leading to dementia such as alzheimer's disease (ad).
PubMedID- 23383391	The recent discovery that mutations in the gene encoding for progranulin (grn) cause frontotemporal lobar degeneration (ftld), and other neurodegenerative diseases leading to dementia, has brought renewed interest in progranulin and its functions in the central nervous system.
PubMedID- 24073234	Alzheimer’s and parkinson’s disease [pd] are the two most common neurodegenerative diseases of the elderly, while dementia with lewy bodies [dlb] is the second-most common form of dementia after alzheimer’s disease [ad].
PubMedID- 21253592	Alzheimer's disease (ad) is the most common form of neurodegenerative disease with dementia in the elderly, affecting approximately 6–8% all persons aged >65 years [1].
PubMedID- 20158567	Alzheimer’s disease (ad) is a neurodegenerative disease leading to dementia that affects approximately 29 million people around the world [1].
PubMedID- 24171818	Alzheimer’s disease (ad) is the most prevalent neurodegenerative disease and cause of dementia in the older population.
PubMedID- 23001356	Second, approximately 20% of mci patients, who progress to dementia, are diagnosed with neurodegenerative diseases other than ad, such as vascular, lewy body, huntington, parkinson, and other dementias [9,11].

Page: 1