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PedAM

Pediatric Disease Annotations & Medicines




Disease dementia
Phenotype C0038868|progressive supranuclear palsy
Sentences 8
PubMedID- 23188965 Others are multiple system atrophy, dementia with lewy bodies, progressive supranuclear palsy, hemi-parkinsonism-hemiatrophy, juvenile parkinsonism with dystonia and hemiatrophy and primary amyloidosis with parkinsonism.
PubMedID- 25853458 Although the patients described here lacked mnd, close relatives presented a wide range of clinical phenotypes including dementia with parkinsonism, progressive supranuclear palsy and als.
PubMedID- 22492994 In a number of neurodegenerative diseases classified as tauopathies, which include frontotemporal dementia with parkinsonism associated with chromosome 17, progressive supranuclear palsy, corticobasal degeneration, and alzheimer's disease (ad), tau becomes hyperphosphorylated and aggregates into filaments, thus losing the ability to bind and stabilize microtubules (4,5).
PubMedID- 24304186 The study employed a cross-disease, cross-species approach to identify mirna that were either specifically dysregulated in msa or were commonly dysregulated in neurodegenerative conditions such as alzheimer's disease, dementia with lewy bodies, progressive supranuclear palsy and corticobasal degeneration or the tg mouse model equivalents of these disorders.
PubMedID- 20798538 Obsessive-compulsive behavior as a symptom of dementia in progressive supranuclear palsy.
PubMedID- 21626553 During the last decades, atypical parkinsonian disorders such as multiple system atrophy, dementia with lewy bodies, progressive supranuclear palsy, and corticobasal degeneration along with secondary parkinsonian disorders have been increasingly recognized as important causes of parkinsonism.
PubMedID- 20129321 Rivastigmine for the treatment of dementia in patients with progressive supranuclear palsy: clinical observations as a basis for power calculations and safety analysis.
PubMedID- 23962722 Hyperphosphorylated tau (p-tau) is the primary component of neurofibrillary tangles (nfts), a pathological hallmark of several neurodegenerative diseases including alzheimer's disease (ad), frontotemporal dementia with parkinsonism associated with chromosome 17, progressive supranuclear palsy, corticobasal degeneration and chronic traumatic encephalopathy, which has recently gained significant attention due to sports- and military-related injuries (1–4).

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