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PedAM

Pediatric Disease Annotations & Medicines




Disease dementia
Phenotype C0020538|hypertension
Sentences 10
PubMedID- 26170844 Moreover, blood adma concentration was increased in hypercholesterolaemia [17], hyperhomocysteinaemia [29, 30], in children with congenital heart disease and pulmonary hypertension [31] and in patients with dementia in the course of cerebral diseases of vascular origin [32, 33].
PubMedID- 24520843 The prevalence of hypertension in people with dementia remained unchanged between older and more recent studies.
PubMedID- 22229084 Age-adjusted hazard ratios (hrs) of dementia associated with hypertension were estimated using cox proportional hazard regression analysis with age at study entry being the age when the baseline survey was completed and the event of interest being age at dementia.
PubMedID- 24851209 However, a considerable number of studies examining the relationships between hypertension with dementia and cognitive decline have reported inconsistent results.
PubMedID- 24520876 Found inconclusive results when comparing medications for diabetes, hypertension or hyperlipidemia in patients with dementia compared to controls [35].
PubMedID- 25962184 First, increasing evidence has suggested that antihypertensive agents have a decreased risk of dementia in individuals with hypertension and antihypertensive treatments need to be carried out in early stage[25], for example, acei and nilvadipine could improve the cerebral blood flow, improve memory and executive function.
PubMedID- 21259046 Since this occlusion induces just mild ischemia, the resulting dnd may be an appropriate animal model for dementia in patient with essential hypertension exposed to small ischemic insults.
PubMedID- 24196416 We found no evidence to confirm or refute the hypothesis that treatment of hypertension in people with dementia leads to overall health benefit.
PubMedID- 25097514 Besides affecting brain atrophy significantly, hypertension also influences regulation of cognitive function and dementia eventually.5-7 high blood pressure level accelerates the aggravation of mild cognitive dysfunction, and leads to cardiovascular and cerebrovascular insufficiency and devastating diseases finally by inducing vascular lesions such as intimal hyperplasia, vascular spasm and endothelial dysfunction.8 considering that intracranial trauma is commonly accompanied by cognitive dysfunction without the influencing factors clarified hitherto,9,10 we herein studied the effects of blood pressure levels on the prognosis of such patients.
PubMedID- 23460043 In multivariate regression models that considered age, sex, preexisting comorbidities including cad, hypertension, history of stroke, af, dementia, ckd ≥ 3 stage, asa score ≥ 3, and smoking status, having cvd was a strong independent predictor of postoperative myocardial injury (ctni rise) (or 6.13, 95% ci 1.57–24.00; p = 0.009) and prolonged hospital stay (los > 20 days) (or 4.27, 95% ci 1.53–11.88; p = 0.005).

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