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PedAM

Pediatric Disease Annotations & Medicines




Disease dementia
Phenotype C0011849|diabetes mellitus
Sentences 24
PubMedID- 25900428 Objective: the aim of this study is to assess whether diabetes mellitus is associated with overall dementia and its subtypes (alzheimer's disease and vascular dementia) among the elderly and to identify the role of cerebrovascular disease in the association between diabetes and dementia.
PubMedID- 22701197 To evaluate the association of apolipoprotein e4 (apoe4) in alzheimer's dementia (ad) with comorbid diabetes mellitus (dm).
PubMedID- 23945905 Importance: depression has been identified as a risk factor for dementia among patients with type 2 diabetes mellitus but the cognitive domains and patient groups most affected have not been identified.
PubMedID- 20829391 Impairment of insulin and igf-i signaling in the brain is one of the causes of dementia associated with diabetes mellitus and alzheimer's disease.
PubMedID- 22521970 Antihypertensive drug use and the risk of dementia in patients with diabetes mellitus.
PubMedID- 26381432 1109 subjects with t2dm were initially screened with american diabetes association criteria for diagnosis of diabetes mellitus and were diagnosed with mci and dementia according to the criteria of dsm-iiir.
PubMedID- 20044657 Only diabetes mellitus was associated with progression to dementia (hazard ratio 2.9, 95% ci 1.1-7.3) after adjustment for sociodemographic factors, apoe4, premorbid iq and other health conditions.
PubMedID- 25954754 This also means that membrane transporters, including ion channels and transporters, are very important therapeutic targets in several diseases such as cardiovascular disorders, hypertension, dementia, metabolic syndrome associated with diabetes mellitus, and cancer.
PubMedID- 26233574 Association between comorbidities and dementia in diabetes mellitus patients: population-based retrospective cohort study.
PubMedID- 25440562 Apolipoprotein e4 allele frequency was highest in dementia with comorbid diabetes mellitus type 2 (0.26).
PubMedID- 20229808 Therefore, insulin sensitizers may have one of the effective measures of the prevention of both types of dementia in people with diabetes mellitus.
PubMedID- 21948010 Aim: to determine the risk of developing dementia in subjects with type 2 diabetes mellitus.
PubMedID- 25941422 Preliminary results of highly localized plantar irradiation with low incident levels of mid-infrared energy which contributes to the prevention of dementia associated with underlying diabetes mellitus.
PubMedID- 24623199 Furthermore, novel therapeutic strategies will be needed to prevent or reduce the development of dementia in people with diabetes mellitus.
PubMedID- 24622366 Interpretation: to the best of our knowledge, this is the first risk score for the prediction of 10 year dementia risk in patients with type 2 diabetes mellitus.
PubMedID- 23003116 Hypoglycaemic episodes and risk of dementia in diabetes mellitus: 7-year follow-up study.
PubMedID- 23299282 Risk factors for dementia with type 2 diabetes mellitus among elderly people in china.
PubMedID- 23691800 The association between diabetes mellitus and the risk of developing dementia has received much attention in epidemiological studies.
PubMedID- 24843645 Reviewed the risk of dementia in diabetes mellitus, indicating that atherosclerosis such as brain infarction, microvascular disease due to insidious ischemia, advanced protein glycation and oxidative stress due to glucose toxicity, and insufficient insulin action were major factors, and the added involvement of aging and genetic factors leads to dementia1.
PubMedID- 24339978 Moreover several studies have reported an increased risk of dementia in subjects with non-insulin-dependent diabetes mellitus [50].
PubMedID- 23428182 The breakdown of the blood-brain barrier (bbb) is associated with dementia in patients with type 2 diabetes mellitus (t2dm).
PubMedID- 21070531 The rotterdam study and others that followed suggested an increased risk to develop dementia and ad in patients with type 2 diabetes mellitus (41,42).
PubMedID- 22411248 The prevalence of type 2 diabetes mellitus (t2dm) increases with age and dementia also increases its incidence in later life.
PubMedID- 24843511 Further examination of the results of large scale, longstanding research, such as the dcct/edic study, is expected to clarify the respective mechanisms and help the prevention of dementia in people with diabetes mellitus.

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