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PedAM

Pediatric Disease Annotations & Medicines




Disease cystic fibrosis
Phenotype C0034069|pulmonary fibrosis
Sentences 4
PubMedID- 20712568 They have been focused on chronic obstructive pulmonary disease, acute respiratory distress syndrome, acute lung injury, pulmonary fibrosis, alteration of lung function in cystic fibrosis, as well as asthma and cachexia in lung cancer patients.
PubMedID- 23523785 This data identifies ceramide as a key molecule associated with pulmonary fibrosis in cystic fibrosis mice and demonstrate for the first time that prolonged inhibition of acid sphingomyelinase is able to attenuate fibrosis and inflammation in this animal model.
PubMedID- 24325216 Copd = chronic obstructive pulmonary disease, cf = cystic fibrosis, a1at = alpha-1antitrypsin deficiency with emphysema, ipf = idiopathic pulmonary fibrosis, pah = pulmonary arterial hypertension, gvhd = graft-versus-host disease.
PubMedID- 20827647 In end-stage cystic fibrosis and patients with idiopathic pulmonary fibrosis, alternative treatment options are currently not available and lung transplantation is indicated.

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