PedAM
Pediatric Disease Annotations & Medicines
| Disease | cystic fibrosis |
| Phenotype | C0016412|folic acid deficiency |
| Sentences | 1 |
| PubMedID- 21753892 | Historically, hyperuricemia, and hyperuricosuria, which leads to dysuria and uric acid crystaluria, have been reported in cystic fibrosis patients with older formulations.135 folic acid deficiency has been associated with use of pancreatin extracts which may form insoluble complexes with folate.76 irritation of the oral mucosa may be avoided by not chewing the medications, or mixing them in foods with a ph > 4.5 (package inserts). |
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