PedAM
Pediatric Disease Annotations & Medicines
| Disease | cryptorchidism |
| Phenotype | C0021359|infertility |
| Sentences | 4 |
| PubMedID- 22832057 | cryptorchidism is associated with male infertility due to germ cell loss in response to elevated temperature. |
| PubMedID- 26472740 | Although several factors can lead to male infertility, such as malformations of the reproductive tract (cryptorchidism or varicocele, orchitis, karyotype anomalies, hypogonadotrophic hypogonadism and y chromosome microdeletions), infection, and chemical exposure34567, 50–70% of male infertility is of unknown etiology, much of which is possibly genetic. |
| PubMedID- 21955839 | On the other hand, we obtained an unexpected finding of a strong difference between familial (but not sporadic) cryptorchidism (and/or with history of infertility within these families) and healthy controls, showing a high risk for hla-drb1*11 bearers. |
| PubMedID- 24466401 | Because cryptorchidism is associated with infertility, malignancy, and cosmetic concerns, orchiopexy has been proven necessary to prevent such conditions. |
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