PedAM
Pediatric Disease Annotations & Medicines
| Disease | crohn disease |
| Phenotype | C0270612|leukoencephalopathy |
| Sentences | 3 |
| PubMedID- 20565845 | Due to detailed brain autopsies, natalizumab, a novel antibody directed to the adhesion molecule a4 integrin, was identified as a risk factor for development of progressive multifocal leukoencephalopathy in patients with crohn's disease or multiple sclerosis treated with this drug [28]. |
| PubMedID- 20594122 | There have been reports of progressive multifocal leukoencephalopathy after treatment with natalizumab in crohn's disease and multiple sclerosis. |
| PubMedID- 23232602 | Objective: natalizumab, a highly effective treatment for multiple sclerosis (ms) and crohn's disease, is associated with progressive multifocal leukoencephalopathy (pml). |
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