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PedAM

Pediatric Disease Annotations & Medicines




Disease crohn disease
Phenotype C0009319|colitis
Sentences 22
PubMedID- 23170145 Ulcerative colitis (uc) together with crohn's disease (cd) are the major phenotypes of the idiopathic inflammatory bowel disease (ibd), which afflicts millions of individuals throughout the world with symptoms that impair quality of life and ability to function.1 currently, the etiology of uc is not well understood, but mucosal tissue edema, increased gut epithelial cell permeability, and extensive infiltration of the colonic mucosa by leucocytes of the myeloid lineage are major pathologic features of this immune disorder.
PubMedID- 23498833 Case report: crohn's-like mycophenolate-induced colitis, a fallout in steroid-free regimens.
PubMedID- 24671169 Although not tested here, based on our data, we suggest that hcmv colitis in patients with crohn's disease could represent a specific outcome of virus-host interaction in a subset of patients that carry mutations in the nod2 gene.
PubMedID- 19639557 Atrioventricular block associated with crohn's relapsing colitis in a 12-year-old child.
PubMedID- 23251142 In conclusion, it has been shown that colonic inflammation regulates the expression of several nuclear receptors in mat in a model of colitis and in patients with crohn's disease.
PubMedID- 22107137 Methods: data from 52 ulcerative colitis (uc) patients with 32 crohn's disease (cd) patients were compared.
PubMedID- 25412586 Recently, it has been reported that crohn's-like intractable colitis occurred in approximately 20% of the patients with xiap deficiency, also known as x-linked lymphoproliferative disease type 2.
PubMedID- 25945443 Many studies have shown that chemokine (c-x-c motif) receptor (cxcr)3 and its ligand chemokines, as monokine induced by interferon (ifn)-gamma (mig), interferon-gamma inducible protein (ip-10) and ifn-inducible t cell-alpha chemoattractant (i-tac), are strongly overexpressed both in the intestinal mucosa of mice with experimental colitis, and in patients with crohn's disease (cd) in lymphocytes, in macrophages and in epithelial cells.
PubMedID- 20232408 Cmv colitis is rare in patients with crohn's disease or mild-moderate ulcerative colitis.
PubMedID- 20567556 Herpes simplex virus colitis complicating the course of a patient with crohn's disease and cirrhosis: an underestimated association.
PubMedID- 24356810 Regulation of anergy-related ubiquitin e3 ligase, grail, in murine models of colitis and patients with crohn's disease.
PubMedID- 20798165 Interleukin-10 gene-deficient (il10(-/-)) mice show a hyper-reaction to normal intestinal bacteria and develop spontaneous colitis similar to that of human crohn's disease when raised under conventional (but not germ-free) conditions.
PubMedID- 24507162 Nineteen patients had crohn's disease, 16 with ulcerative colitis (uc), and one with indeterminate colitis.
PubMedID- 21698892 crohn's disease (cd) together with ulcerative colitis (uc) and indeterminate colitis (ic) are the so called inflammatory bowel diseases (ibd).
PubMedID- 22703461 Letter: pathogenicity of th17 cells may differ in ulcerative colitis compared with crohn's disease.
PubMedID- 22759851 Ulcerative colitis (uc) together with crohn's disease (cd) belongs to inflammatory bowel diseases (ibd).
PubMedID- 23345025 Anti-pr3 anca were significantly more prevalent (p < 0.0001) and their titers significantly higher (p < 0.0001) among ulcerative colitis compared with crohn's disease patients.
PubMedID- 21345224 The graphs illustrate a significant increase in both the proportion (ttest p = 0.0017) and intensity (ttest p = 0.0013) of fascin immunoreactivity in crohn's compared with ulcerative colitis samples.
PubMedID- 20567555 Herpes simplex virus colitis in a patient with crohn's disease and hepatitis b and d cirrhosis.
PubMedID- 23519342 Paratuberculosis lipophilic antigen causes crohn's disease-type necrotizing colitis in mice.
PubMedID- 21436303 crohn's disease (cd), together with ulcerative colitis, has been a principal beneficiary of this technology with a recent meta-analysis from the international ibd genetics consortium increasing the number of confirmed cd susceptibility loci to 71.
PubMedID- 26406496 A. expression was monitored in synovial fluid macrophages from healthy individuals (blue) or patients suffering from rheumatoid arthritis (red); b. expression was monitored in skeletal muscle fibers from healthy individuals (blue), dermatomyositis patients (red), polymyositis patients (gold), and inclusion body myositis patients (green); c. expression was monitored in peripheral blood mononuclear cells from healthy individuals (blue), patients suffering from ulcerative colitis (red), or of crohn's disease (gold).

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