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PedAM

Pediatric Disease Annotations & Medicines




Disease constipation
Phenotype C0007222|cardiovascular disease
Sentences 2
PubMedID- 23506618 However, the question remains - why are the more severe forms of non-pathological chronic constipation associated with cardiovascular disease risk even when other lifestyle variables (diet, medications, exercise, etc.)
PubMedID- 26197999 However, given the association between symptoms of constipation with cardiovascular disease and t2dm, it seems that an ibat inhibitor like elobixibat, in addition to positive effects on symptoms and signs of constipation, may provide positive metabolic side effects reducing the risk for cvd and t2dm.

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