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PedAM

Pediatric Disease Annotations & Medicines




Disease complement deficiency
Phenotype C0025303|meningococcal disease
Sentences 2
PubMedID- 24104403 An apparent strong association between complement deficiencies and invasive neisserial infections prompted several studies to estimate the frequency of complement deficiencies among patients with their first episode of systemic neisserial infection.91,114-126 figueroa and densen31 studied the correlation between the incidence of complement deficiency in patients with meningococcal disease vs. the incidence of meningococcal disease in the general population and showed that the rate of complement deficiencies detected dropped in areas the incidence of disease was high.
PubMedID- 24265955 Therefore, in the future, evidence-based regulations for disability discharge from the military service or for transfer to different military bases are necessary taking into consideration the current circumstances that there is a high recurrence rate in meningococcal disease with complement deficiency and the 100% efficacy of the vaccine is not expected even with vaccination [19].

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