PedAM
Pediatric Disease Annotations & Medicines
| Disease | colorectal neoplasms |
| Phenotype | C0009319|colitis |
| Sentences | 5 |
| PubMedID- 24907505 | We included studies on thiopurine exposure and risk of colorectal neoplasia in patients with ulcerative colitis or crohn's disease. |
| PubMedID- 24710620 | 5-aminosalicylates use was associated with a reduced risk of colorectal neoplasia in patients with ulcerative colitis (or 0.63; 95%ci 0.48-0.84). |
| PubMedID- 21556038 | Objectives: some studies have suggested that ursodeoxycholic acid (udca) may have a chemopreventive effect on the development of colorectal neoplasia in patients with ulcerative colitis (uc) and primary sclerosing cholangitis (psc). |
| PubMedID- 23867875 | Background: aberrant methylation of the eya4 gene (meya4) highly discriminates ulcerative colitis (uc) cases with colorectal neoplasia from uc controls in both tissue and stool. |
| PubMedID- 20585313 | These data suggest that elevated erbb4 expression in inflammatory bowel disease (13) could contribute to inappropriate cell survival in the inflammatory milieu, thus promoting colitis-associated development of colorectal tumors. |
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