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PedAM

Pediatric Disease Annotations & Medicines




Disease colorectal cancer
Phenotype C1333990|hereditary nonpolyposis colorectal cancer
Sentences 2
PubMedID- 21132538 colorectal cancers associated with the hereditary nonpolyposis colorectal cancer (hnpcc) syndrome are characterized by wide-spread microsatellite instability, but show few gross genomic alterations.
PubMedID- 25213040 Aim: colonic surveillance reduces the lifetime risk of colorectal cancer in patients with lynch syndrome (hereditary nonpolyposis colorectal cancer) from 60 to 80% to 10% and confers a 7-year survival advantage.

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