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PedAM

Pediatric Disease Annotations & Medicines




Disease colorectal cancer
Phenotype C0494165|liver metastasis
Sentences 105
PubMedID- 24760176 Downregulation of mir-214 is specific of liver metastasis in colorectal cancer and could play a role determining the metastatic niche.
PubMedID- 21390153 Hbv infection decreases risk of liver metastasis in patients with colorectal cancer: a cohort study.
PubMedID- 23801208 Conclusions: decrease of the number of t lymphocyte and mast cell may play an important role in local infiltration of immune microenvironment of stage iii to iiii colorectal cancer with liver metastasis.
PubMedID- 22783377 Additionally, these profiles may be useful predictors in the identification of eligible colorectal cancer patients with liver metastasis for folfox treatment.
PubMedID- 22736138 Multivariate cox analysis showed that sncg expression was an independent prognostic factor for colorectal cancer with synchronous liver metastasis(rr=1.97, 95%ci:1.10-3.53, p<0.05).
PubMedID- 23741223 Surgery is the first choice for liver metastasis of colorectal cancer [4], but only 15–35% of patients have indications for hepatectomy [5, 6].
PubMedID- 20977728 [20] analyzed predictors of survival after hepatic resection in colorectal cancer patients with liver metastasis, and they reported age, primary tumor grade, comorbidity score, and chemotherapy after liver resection to be significant prognostic factors.
PubMedID- 23991968 Patients and methods: ve of liver metastases was performed by manual contouring before and after chemotherapy on 45 pairs of computed tomography (ct) images in 36 patients who suffered from metastatic colorectal cancer (mcrc) with liver metastasis only.
PubMedID- 24263311 Predictive factors for the benefit of perioperative folfox for resectable liver metastasis in colorectal cancer patients (eortc intergroup trial 40983).
PubMedID- 25731265 [detection of hepatic lymph node involvement by pet/ct in colorectal cancer patients with liver metastasis].
PubMedID- 20731024 Aim: to investigate the serological diagnostic factors for liver metastasis in patients with colorectal cancer.
PubMedID- 25826583 Moreover, in an in vivo metastasis model, sapril-bp reduced liver metastasis of colorectal cancer cells.
PubMedID- 23980038 [consideration of therapy for colorectal cancer with synchronous unresectable liver metastasis].
PubMedID- 24747592 Control normal liver tissues (nls) showing no unusual histological features were also obtained from surgically resected materials obtained from 8 patients with liver metastasis of colorectal cancer.
PubMedID- 21780098 Pharmacokinetic parameters from 3-tesla dce-mri as surrogate biomarkers of antitumor effects of bevacizumab plus folfiri in colorectal cancer with liver metastasis.
PubMedID- 24755295 Mir-181a demonstrated overexpression in colorectal cancer with liver metastasis.
PubMedID- 22138292 [surgical treatment of liver metastasis in patients with colorectal cancer].
PubMedID- 22850548 Background: when anti-vegf (vascular endothelial growth factor) antibody bevacizumab is applied in neoadjuvant treatment of colorectal cancer patients with liver metastasis, 5-6 weeks between last bevacizumab dose and liver resection are currently recommended to avoid complications in wound and liver regeneration.
PubMedID- 25436346 In our department, perioperative chemotherapy was introduced for the treatment of colorectal cancer associated with resectable synchronous liver metastasis.
PubMedID- 20422876 Effect of hepatocyte growth factor on progression of liver metastasis in colorectal cancer.
PubMedID- 23356713 The hr for colorectal cancer with liver metastasis was 0.42 but those from prostate (0.25) and breast (0.31) cancer were even more favorable.
PubMedID- 21624121 Ccl20 and/or ccr6 expression have been reported in pancreatic and colorectal cancer and correlates with invasion and liver metastasis [20-22].
PubMedID- 25889950 One hundred and fifty-nine patients who underwent hepatic metastasectomy with curative intent for liver metastasis of colorectal cancer between october 1991 and december 2006 were enrolled.
PubMedID- 20683000 Overexpression of mmp-13 gene in colorectal cancer with liver metastasis.
PubMedID- 24518602 Similarly, high serum levels of scxcl16 in colorectal cancer patients were associated with recurrent liver metastasis and poor prognosis (matsushita et al, 2012).
PubMedID- 24452736 In colorectal cancer with simultaneous liver metastasis, leen et al (10) demonstrated that the hepatic arterial blood flow was significantly increased and the portal blood flow was significantly decreased in comparison with that observed in healthy volunteers using doppler ultrasonography.
PubMedID- 20206548 Current data support the use of hepatectomy for well-selected elderly colorectal cancer patients with liver metastasis; however, this and other evolving therapies need to be assessed in the elderly to better define their role, indications, safety and outcomes.
PubMedID- 23898232 There are few well-organized reports because t1 colorectal cancer with synchronous liver metastasis is extremely rare.
PubMedID- 20087616 Treatment results of folfox chemotherapy before surgery for lymph node metastasis of advanced colorectal cancer with synchronous liver metastasis: the status of ln metastasis and vessel invasions at the primary site in patients who responded to folfox.
PubMedID- 26050227 Aberrant expression of long noncoding rnas in colorectal cancer with liver metastasis.
PubMedID- 21152140 Nevertheless, in a study that evaluated the usefulness of chest ct for the assessment of the presence of pulmonary metastasis prior to a lung metastasectomy in colorectal cancer patients with liver metastasis, the positive prediction rate was not significantly different from that for chest radiography; thus, its usefulness was low [14].
PubMedID- 25785086 Initial hepatic artery infusion and systemic chemotherapy for asymptomatic colorectal cancer with un-resectable liver metastasis.
PubMedID- 22505647 High expression of il-13 receptor alpha2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.
PubMedID- 23484984 Common causes include viral infection and autoimmune disease.1 colorectal cancer with liver metastasis and itp is a rare clinical scenario; only three cases have been reported in the english literature.2,3 adverse effects of adjuvant chemotherapy for liver metastasis may aggravate itp.4 the sequencing of chemotherapy, operation for the primary and liver metastasis, and splenectomy is important.
PubMedID- 20945037 Prognosis of colorectal cancer with liver metastasis: value of a prognostic index.
PubMedID- 24129181 Significant overexpression of dvl1 in taiwanese colorectal cancer patients with liver metastasis.
PubMedID- 19508508 Prognostic factors in survival of colorectal cancer patients with synchronous liver metastasis.
PubMedID- 20204382 Conclusions: cd10 expression is a significant risk factor for liver metastasis in patients with colorectal cancer and is correlated with prognosis.
PubMedID- 23268036 Even in the era of new anticancer drugs, an optimal treatment strategy for colorectal cancer associated with liver metastasis and peritoneal carcinomatosis has yet to be established.
PubMedID- 23721165 Establishment of a predictive genetic model for estimating chemotherapy sensitivity of colorectal cancer with synchronous liver metastasis.
PubMedID- 25970784 The serum il6 and il8 levels were significantly increased in the colorectal cancer patients with liver metastasis [43].
PubMedID- 24324891 Similar results were published by vogl and coworkers in 2009 [23] and pohlen and coworkers in 2006 [27] for patients with liver metastasis of colorectal cancer.
PubMedID- 25436344 Conclusions: racical resection is the key to improve the long-term survival rate of colorectal cancer with liver metastasis.
PubMedID- 26108758 For the patients who have colorectal cancer with liver metastasis, synchronous resection or staged surgery for primary colorectal tumor and liver metastasis is usually needed which is associated with significant trauma.
PubMedID- 24953371 [association of expression of hgf and its receptor c-met to primary colorectal cancers with synchronous liver metastasis].
PubMedID- 25326396 Pulmonary metastasectomy in colorectal cancer patients with previously resected liver metastasis: pooled analysis.
PubMedID- 23443137 liver metastasis in colorectal cancer is the major cause of cancer-related deaths.
PubMedID- 24334302 Apoptotic circulating tumor cells (ctcs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not ctcs.
PubMedID- 20569697 Here, we identified a subpopulation of cd26(+) cells uniformly present in both the primary and metastatic tumors in colorectal cancer patients with liver metastasis.
PubMedID- 24653631 Differential expression of serum mir-126, mir-141 and mir-21 as novel biomarkers for early detection of liver metastasis in colorectal cancer.

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