PedAM
Pediatric Disease Annotations & Medicines
| Disease | colorectal cancer |
| Phenotype | C0494165|liver metastases |
| Sentences | 110 |
| PubMedID- 22962603 | Firstly, we validated the suppression of mir-214 in human hcc by real-time quantitative rt-pcr (qrt-pcr) in 20 paired tumor and non-tumor liver tissues of hcc patients and 10 histologically normal liver tissues from colorectal cancer patients with liver metastases. |
| PubMedID- 22206922 | Background: intensive medical treatment increases resection rate of liver metastases in patients with metastatic colorectal cancer (mcrc). |
| PubMedID- 20649733 | Objective: to evaluate the effect of prophylactic regional liver chemotherapy during the perioperative period on improving survival and preventing liver metastases in patients with colorectal cancer (crc). |
| PubMedID- 22850548 | Methods: fifty colorectal cancer patients with liver metastases received neoadjuvant chemotherapy +/- bevacizumab supplementation. |
| PubMedID- 24699568 | The formation of liver metastases in colorectal cancer patients is the primary cause of patient death. |
| PubMedID- 22242554 | Traditionally, resection of the primary tumor has been advocated in order to prevent complications of the primary tumor colorectal cancer in patients with synchronous liver metastases. |
| PubMedID- 22209659 | Incidence of synchronous liver metastases in patients with colorectal cancer in relationship to clinico-pathologic characteristics. |
| PubMedID- 20110289 | Patients and methods: colorectal cancer patients with isolated liver metastases, who underwent ihp, were included in this study. |
| PubMedID- 22560316 | Study design: we conducted a retrospective cohort study of consecutive colorectal cancer patients with resectable synchronous liver metastases treated between 1993 and 2010, constructing a decision tree comparing simultaneous and staged resections. |
| PubMedID- 26222850 | Secondly, previous studies on colorectal cancer with liver metastases indicated that patients with extra hepatic metastases had poor survival,16,17 and some patients with extra hepatic metastases were included in the current study. |
| PubMedID- 20977728 | Conclusions: although limited by small case number, this study demonstrated a possible role of whole-liver rt in improving hepatic dysfunction and delaying mortality from hepatic failure for end-stage colorectal cancer patients with massive liver metastases. |
| PubMedID- 26566221 | Early assessment of colorectal cancer patients with liver metastases treated with antiangiogenic drugs: the role of intravoxel incoherent motion in diffusion-weighted imaging. |
| PubMedID- 24659854 | Many surgeons support a simultaneous approach as a safe treatment to liver metastases due to colorectal cancer [62–64]. |
| PubMedID- 22409860 | One hundred twenty colorectal cancer patients with liver metastases (100 with synchronous metastases, 20 with metachronous) were evaluated. |
| PubMedID- 21938482 | Previous studies have suggested that plasma endostatin levels are elevated in colorectal cancer patients with liver metastases [20]. |
| PubMedID- 21780098 | We conducted a phase ii trial to confirm the pharmacokinetic parameters from 3-tesla dynamic contrast-enhanced magnetic resonance imaging (dce-mri) as surrogate biomarkers of bv + folfiri regimen efficacy in colorectal cancer with liver metastases. |
| PubMedID- 20617435 | In a study in colorectal cancer patients with liver metastases, the liver metastases in 9 of 12 patients were visualized with 111in-bevacizumab (fig. |
| PubMedID- 24358218 | liver metastases of human colorectal cancer cells were generated by intrasplenic (isp) injections of 1×105 t-hct 116 cells and 1×106 hct 116 cells into brg nude mice (n = 3 and 3, respectively), followed by splenectomy under isoflurane anesthesia [4]. |
| PubMedID- 23876227 | An elevated nlr in colorectal cancer patients with liver metastases receiving only neoadjuvant chemotherapy before surgical resection of liver metastases predicted worse rate of survival [11]. |
| PubMedID- 22993665 | Fifteen percent to twenty-five percent of patients affected by colorectal cancer presents with liver metastases at diagnosis. |
| PubMedID- 20821329 | This work investigated 5fu pharmacokinetics in liver metastases of colorectal cancer. |
| PubMedID- 25061576 | Prognostic and predictive value of liver volume in colorectal cancer patients with unresectable liver metastases. |
| PubMedID- 23497123 | We compared three groups, composed of 17 colorectal cancer patients with liver metastases who had undergone at least segmental anatomical hepatic resection (8 patients with and 9 patients without preoperative chemotherapy) and 15 patients in a living liver donor transplantation group in our department since january 2008. the preoperative chemotherapy regimen was oxaliplatin-based in six subjects, irinotecan-based in one subject, and oxaliplatin- and irinotecan-based in one subject. |
| PubMedID- 25692420 | High expression of darpp-32 in colorectal cancer is associated with liver metastases and predicts survival for dukes a and b patients: results of a pilot study. |
| PubMedID- 24267032 | Nine male patients with liver metastases of colorectal cancer were included retrospectively (age, 48 to 76 years (mean 62.8); weight, 73 to 100 kg (mean 85.5)). |
| PubMedID- 21084828 | Most colorectal cancer patients with liver metastases are not resectable upon initial diagnosis. |
| PubMedID- 25081377 | Cryoablation plus chemotherapy in colorectal cancer patients with liver metastases. |
| PubMedID- 19508508 | Aim: to determine the factors affecting the survival in colorectal cancer patients with synchronous liver metastases. |
| PubMedID- 23035809 | Background: liver resection provides one of the best oncological outcomes for liver metastases in patients with colorectal cancer. |
| PubMedID- 25058762 | Simultaneous laparoscopic colectomy and hepatectomy for primary colorectal cancer with synchronous liver metastases appears feasible with low morbidity and favorable outcomes. |
| PubMedID- 23302476 | Objectives: to analyze the survival outcomes of the surgery for colorectal cancer with liver metastases (crclm), and study the mode of multi-disciplinary team (mdt) for crclm. |
| PubMedID- 22216763 | Background: selective internal radiation therapy (sirt) is a new and effective locoregional anticancer therapy for colorectal cancer patients with liver metastases. |
| PubMedID- 21126340 | Specific genomic aberrations in primary colorectal cancer are associated with liver metastases. |
| PubMedID- 25089107 | Methods: colorectal cancer patients with liver metastases resected at the ottawa hospital between january 1, 2003, and december 31, 2009, were identified, and their clinical records were retrospectively reviewed. |
| PubMedID- 24203162 | Interestingly, the expression of both pparβ/δ and cox-2 in tissues of colorectal cancer patients leads to liver metastases, a condition associated with poor prognosis (yoshinaga et al, 2011). |
| PubMedID- 22934251 | To address this question, sequential lung or sequential liver metastases of colorectal cancer patients were analyzed using whole slide image quantification after immunohistochemical staining against cd3, cd8, foxp3, cd68 and granzyme b. the clinical data and interventions were associated with each individual patient and the metastatic lesions. |
| PubMedID- 24606532 | Pure laparoscopic right-sided hepatectomy in the semi-prone position for synchronous colorectal cancer with liver metastases. |
| PubMedID- 25622583 | Objective: to explore the feasibility and safety of laparoscopic radical coloproctectomy and hepatectomy for resectalble colorectal cancer with liver metastases (crclm), and evaluate the survival outcomes of short-middle term for these patients. |
| PubMedID- 23047645 | Hmgb1 is a valuable serum biomarker for early estimation of therapy response and prognosis in colorectal cancer patients with liver metastases undergoing re therapy. |
| PubMedID- 23700570 | The response rate was approximately 20%, and it was difficult to expect long-term survival for most unresectable colorectal cancer patients with liver metastases [31]. |
| PubMedID- 25297902 | Is liver transplantation an option in colorectal cancer patients with nonresectable liver metastases and progression on all lines of standard chemotherapy. |
| PubMedID- 22537902 | colorectal cancer with synchronous liver metastases: does global management at the same centre improve results. |
| PubMedID- 23022595 | Two studies found that for liver metastases of colorectal cancer, non-responding lesions had significantly lower pre-treatment mean adcs than responding lesions[36,37], but this was not confirmed in a third study[38]. |
| PubMedID- 24106681 | Prospective multicenter phase ii clinical trial of folfiri chemotherapy as a neoadjuvant treatment for colorectal cancer with multiple liver metastases. |
| PubMedID- 22811880 | The management of colorectal cancer patients with liver metastases is a common clinical problem. |
| PubMedID- 24081807 | Cause of death from liver metastases in colorectal cancer. |
| PubMedID- 23815814 | In colorectal cancer with early liver metastases, co-expression of cd133 and cd44 is significantly higher when compared to those without early liver metastases [48]. |
| PubMedID- 23497553 | The investigated patient group included nine male subjects with liver metastases of colorectal cancer (mean age 62.8 years, range 48 to 76). |
| PubMedID- 24394015 | As the present case is considered rare, we herein review our previous report on a case of early colorectal cancer with synchronous multiple liver metastases. |
| PubMedID- 23268036 | [a long-term survivor of colorectal cancer associated with multiple liver metastases and peritoneal carcinomatosis treated through a multidisciplinary approach]. |